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CAS 19246-24-3

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Telomycin

Description:
Telomycin, with the CAS number 19246-24-3, is a naturally occurring antibiotic that belongs to the class of compounds known as macrolides. It is produced by the fermentation of certain strains of Streptomyces bacteria. Telomycin exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive bacteria, making it valuable in clinical settings for treating various infections. The compound is characterized by its complex macrolide structure, which includes a large lactone ring and multiple sugar moieties that contribute to its biological activity. Telomycin's mechanism of action primarily involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of susceptible bacteria. Additionally, telomycin has shown potential in research for its immunomodulatory effects and may have applications beyond its antibiotic properties. However, like many antibiotics, its use is subject to considerations of resistance and side effects, necessitating careful clinical application.
Formula:C60H79N13O19
InChI:InChI=1/C60H79N13O19/c1-26(2)50(80)47-58(88)73-18-16-42(77)49(73)60(91)92-30(6)35(23-64-53(83)40(25-74)67-43(78)20-36(61)59(89)90)52(82)70-46(29(5)75)56(86)66-28(4)51(81)65-24-44(79)72-17-15-41(76)48(72)57(87)68-39(19-31-21-62-37-13-9-7-11-32(31)37)54(84)69-45(55(85)71-47)27(3)34-22-63-38-14-10-8-12-33(34)38/h7-14,19,21-22,26-30,35-36,40-42,45-50,62-63,74-77,80H,15-18,20,23-25,61H2,1-6H3,(H,64,83)(H,65,81)(H,66,86)(H,67,78)(H,68,87)(H,69,84)(H,70,82)(H,71,85)(H,89,90)
SMILES:CC(C)C(C1C(=O)N2CCC(C2C(=O)OC(C)C(CN=C(C(CO)N=C(CC(C(=O)O)N)O)O)C(=NC(C(C)O)C(=NC(C)C(=NCC(=O)N2CCC(C2C(=NC(=Cc2c[nH]c3ccccc23)C(=O)NC(C(C)c2c[nH]c3ccccc23)C(=N1)O)O)O)O)O)O)O)O
Synonyms:
  • A 128
  • Antibiotic 128
  • C-159
  • Nsc 235069
  • beta-aspartyl-N-{[1,19-dihydroxy-12-(1-hydroxyethyl)-24-(1-hydroxy-2-methylpropyl)-27-[1-(1H-indol-3-yl)ethyl]-30-(1H-indol-3-ylmethylidene)-9,16-dimethyl-5,8,11,14,18,23,26,29,32-nonaoxotriacontahydro-18H-dipyrrolo[2,1-c:2',1'-o][1,4,7,10,13,16,19,22,25]oxaoctaazacyclooctacosin-15-yl]methyl}serinamide
  • TELOMYCIN
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