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CAS 192461-96-4

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8,9-Dihydroxyeicosatrienoic acid

Description:
8,9-Dihydroxyeicosatrienoic acid (DHETrE) is a bioactive lipid derived from arachidonic acid, characterized by the presence of two hydroxyl groups at the 8 and 9 positions of its eicosatrienoic acid backbone. This compound is part of the family of hydroxyeicosanoids, which are known for their roles in various physiological processes, including inflammation and vascular function. DHETrE is involved in signaling pathways that regulate cellular responses and can influence processes such as angiogenesis and cell proliferation. Its structure allows it to interact with specific receptors and enzymes, contributing to its biological activity. The compound is of interest in pharmacological research due to its potential therapeutic implications in cardiovascular diseases and other conditions linked to dysregulated lipid metabolism. As a relatively specific metabolite, it can serve as a biomarker for certain physiological states or diseases. Overall, 8,9-Dihydroxyeicosatrienoic acid exemplifies the complexity of lipid signaling and its impact on human health.
Formula:C20H34O4
InChI:InChI=1/C20H34O4/c1-2-3-4-5-6-7-8-9-12-15-18(21)19(22)16-13-10-11-14-17-20(23)24/h6-7,9-10,12-13,18-19,21-22H,2-5,8,11,14-17H2,1H3,(H,23,24)/b7-6-,12-9-,13-10-
InChI key:InChIKey=DCJBINATHQHPKO-TYAUOURKNA-N
SMILES:C(C(C/C=C\CCCC(O)=O)O)(C/C=C\C/C=C\CCCCC)O
Synonyms:
  • (5E,11E,14E)-8,9-dihydroxyicosa-5,11,14-trienoic acid
  • (5Z,11Z,14Z)-8,9-Dihydroxy-5,11,14-eicosatrienoic acid
  • 5,11,14-Eicosatrienoic acid, 8,9-dihydroxy-, (5Z,11Z,14Z)-
  • 5,11,14-Eicosatrienoic acid, 8,9-dihydroxy-, (all-Z)-
  • 8,9-Dhet
  • 8,9-Dihydroxyeicosatrienoic acid
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