CAS 192703-06-3

5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide

Description:

The chemical substance known as 5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide, with the CAS number 192703-06-3, is a complex organic compound characterized by its pyrazole core structure, which is substituted at various positions. The presence of a chloro group and multiple methyl groups on the phenyl rings contributes to its unique chemical properties and potential biological activity. The bicyclic structure, specifically the trimethylbicyclo[2.2.1]heptane moiety, adds to the steric and electronic characteristics of the molecule, influencing its interactions in biological systems. This compound may exhibit specific pharmacological activities, making it of interest in medicinal chemistry. Its solubility, stability, and reactivity can vary based on the functional groups present, and it may be subject to various synthetic pathways for its preparation. Overall, this compound represents a class of molecules that could have applications in drug development or other chemical applications.

Formula: C₂₉H₃₄ClN₃O

InChI: InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1

InChI key: InChIKey=SUGVYNSRNKFXQM-XRHWURSXSA-N

SMILES: C[C@@]12[C@H](NC(=O)C=3C=C(N(CC4=CC=C(C)C=C4)N3)C5=CC(C)=C(Cl)C=C5)C(C)(C)[C@@](C1)(CC2)[H]

Synonyms:

• 1H-Pyrazole-3-carboxamide, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-(1,3,3-trimethylbicyclo[2.2.1]hept-2-yl)-, (1S-endo)-
• 1H-pyrazole-3-carboxamide, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-
• 5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide
• Sr 144528

5-(4-Chloro-3-methylphenyl)-1-(4-methylbenzyl)-N-((1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl)-1H-pyrazole-3-carboxamide

CAS: 192703-06-3

Formula: C₂₉H₃₄ClN₃O

Purity: 98%

Molecular weight: 476.0528

Ref: IN-DA002G8I

SR 144528-d7

Controlled Product

CAS: 192703-06-3

Formula: C₂₉D₇H₂₇ClN₃O

Color and Shape: Neat

Molecular weight: 483.096

Ref: TR-S684402

SR 144528

Controlled Product

CAS: 192703-06-3

Formula: C₂₉H₃₄ClN₃O

Color and Shape: Neat

Molecular weight: 476.05

Ref: TR-S684400

SR 144528

Controlled Product

CAS: 192703-06-3

SR 144528 is a cannabinoid receptor antagonist. SR 144528 binds to the cytosolic C a 2 + channel and inhibits the release of Ca 2 + from intracellular stores. This effect results in decreased activation of MMP-9 and reduced production of proinflammatory cytokines. SR 144528 also suppresses mitochondrial membrane potential, leading to cell death by apoptosis. SR 144528 has been shown to have synergistic effects with low doses of glycol ethers, which may be due to its ability to inhibit energy metabolism and receptor activity.

Formula: C₂₉H₃₄CIN₃O

Purity: Min. 98 Area-%

Molecular weight: 476.05 g/mol

Ref: 3D-BS179309

SR144528

CAS: 192703-06-3

SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).

Formula: C₂₉H₃₄ClN₃O

Purity: 99.63%

Color and Shape: Solid

Molecular weight: 476.05

Ref: TM-T16928