
CAS 192704-82-8
:Eplerenone EP Impurity B
Description:
Eplerenone EP Impurity B, with the CAS number 192704-82-8, is a chemical compound that is recognized as an impurity associated with the pharmaceutical agent eplerenone, which is primarily used as an antihypertensive and heart failure treatment. This impurity is characterized by its specific molecular structure, which may differ slightly from the parent compound, potentially affecting its pharmacological properties. Typically, impurities like Eplerenone EP Impurity B are monitored during the drug manufacturing process to ensure product quality and safety. The compound may exhibit distinct physical and chemical properties, such as solubility, stability, and reactivity, which are crucial for its identification and quantification in pharmaceutical formulations. Regulatory guidelines often require the characterization and control of such impurities to comply with safety standards. Understanding the characteristics of impurities is essential for assessing their impact on the efficacy and safety of the final pharmaceutical product.
Formula:C24H30O6
Synonyms:- Eplerenone EP Impurity B
- Eplerenone Impurity 4(Eplerenone EP Impurity B)
- Pregn-4-ene-7,21-dicarboxylic acid, 11,12-epoxy-17-hydroxy-3-oxo-, 21,17-lactone, 7-methyl ester, (7α,11α,12α,17α)-
- Eplerenone Impurity B
- (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
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Eplerenone EP Impurity B
CAS:Formula:C24H30O6Color and Shape:White To Off-White SolidMolecular weight:414.50(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
CAS:<p>Applications (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Formula:C24H30O6Color and Shape:NeatMolecular weight:414.491



