CAS 192725-17-0
:Lopinavir
Description:
Lopinavir is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It belongs to the class of protease inhibitors and is often combined with ritonavir to enhance its efficacy and bioavailability. The chemical formula of Lopinavir is C37H48N4O5, and it has a molecular weight of approximately 628.88 g/mol. Lopinavir is characterized by its complex structure, which includes multiple rings and functional groups that contribute to its pharmacological activity. It is typically administered orally in the form of tablets or a liquid solution. The substance is known for its ability to inhibit the HIV protease enzyme, thereby preventing viral replication. Lopinavir is generally well-tolerated, but it can have side effects, including gastrointestinal disturbances and potential impacts on lipid metabolism. Due to its role in HIV treatment, Lopinavir is often part of combination therapy regimens, which may include other antiretroviral agents to improve treatment outcomes and reduce the risk of resistance.
Formula:C37H48N4O5
InChI:InChI=1/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
InChI key:InChIKey=KJHKTHWMRKYKJE-SUGCFTRWSA-N
SMILES:[C@@H](C(N[C@@H](CC1=CC=CC=C1)C[C@@H]([C@H](CC2=CC=CC=C2)NC(COC3=C(C)C=CC=C3C)=O)O)=O)([C@@H](C)C)N4C(=O)NCCC4
Synonyms:- A 157378.0
- 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
- 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
- (αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
- 1(2H)-Pyrimidineacetamide, N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, [1S-[1R*(R*),3R*,4R*]]-
- ABT 378
- ABT-378
- UNII-2494G1JF75
- Kaletra
- (S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
- (1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
- (2S)-N-[(2S,4S,5S)-5-{[(2,6-dimethylphenoxy)acetyl]amino}-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
- 1(2H)-Pyrimidineacetamide, N-((1S,3S,4S)-4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahyrdo-alpha-1-methylethyl)-2-oxo-, (alphaS)-
- (alphaS)-Tetrahydro-N-((alphaS)-alpha-((2S,3S)-2-hydroxy-4-phenyl-3-(2-(2,6-xylyloxy)acetamido)butyl)phenethyl)-alpha-isopropyl-2-oxo-1(2H)-pyrimidineacetamide
- LOPINAVIR
- Aluviran
- Koletra
- (2S)-N-[(2R,4S,5S)-5-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
- (2s)-n-[(2r,4s,5s)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
- (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
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Found 20 products.
Lopinavir
CAS:Formula:C37H48N4O5Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:628.81LOPINAVIR FOR SYSTEM SUITABILITY CRS
CAS:<p>LOPINAVIR FOR SYSTEM SUITABILITY CRS</p>Formula:C37H48N4O5Molecular weight:628.8008LOPINAVIR FOR PEAK IDENTIFICATION CRS
CAS:<p>LOPINAVIR FOR PEAK IDENTIFICATION CRS</p>Formula:C37H48N4O5Molecular weight:628.8008Lopinavir
CAS:<p>Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure</p>Formula:C37H48N4O5Color and Shape:White Off-White PowderMolecular weight:628.36247(2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
CAS:Formula:C37H48N4O5Purity:%Color and Shape:SolidMolecular weight:628.8008Ref: IN-DA003RD4
1g158.00€5gTo inquire100gTo inquire10mg30.00€25mg50.00€50mg50.00€100mg65.00€250mg99.00€Lopinavir EP Impurity H
CAS:Formula:C29H32N2O4Color and Shape:White To Off-White SolidMolecular weight:472.58Lopinavir
CAS:Formula:C37H48N4O5Purity:≥ 98.0% (anhydrous basis)Color and Shape:White crystalline powderMolecular weight:628.80Lopinavir
CAS:<p>Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.</p>Formula:C37H48N4O5Purity:98% - 99.62%Color and Shape:White Crystalline SolidMolecular weight:628.8Lopinavir
CAS:<p>Stability Hygroscopic<br>Applications A selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.<br>References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)<br></p>Formula:C37H48N4O5Color and Shape:White SolidMolecular weight:628.80Lopinavir
CAS:<p>Anti-viral; HIV protease inhibitor</p>Formula:C37H48N4O5Purity:Min. 97.5 Area-%Color and Shape:White Off-White PowderMolecular weight:628.8 g/molLopinavir - Bio-X ™
CAS:<p>Chemically derived from ritonavir, Lopinavir belongs to the amphetamines. Lopinavir is clinically used in the prevention and treatment of HIV infections as it acts as HIV-1 protease inhibitor. In 2020, lopinavir was tested to treat COVID-19 patients and although it led to a higher rate of gastrointestinal side effects, the Lopinavir-treated group had a lower incidence of severe complications. Overall it was deemed not to work as a treatment.</p>Formula:C37H48N4O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:628.8 g/molN5-Des[(2,6-dimethylphenoxy)acetyl] N5-Formal Lopinavir
CAS:Controlled ProductFormula:C28H38N4O4Color and Shape:NeatMolecular weight:494.63Ref: 10-F079428
Discontinued product
![(2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003RD4.jpg&w=3840&q=75)
![N5-Des[(2,6-dimethylphenoxy)acetyl] N5-Formal Lopinavir](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FD288205.jpg&w=3840&q=75)
