CAS 192725-17-0: Lopinavir

Description:Lopinavir is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It belongs to the class of protease inhibitors and is often combined with ritonavir to enhance its efficacy and bioavailability. The chemical formula of Lopinavir is C37H48N4O5, and it has a molecular weight of approximately 628.88 g/mol. Lopinavir is characterized by its complex structure, which includes multiple rings and functional groups that contribute to its pharmacological activity. It is typically administered orally in the form of tablets or a liquid solution. The substance is known for its ability to inhibit the HIV protease enzyme, thereby preventing viral replication. Lopinavir is generally well-tolerated, but it can have side effects, including gastrointestinal disturbances and potential impacts on lipid metabolism. Due to its role in HIV treatment, Lopinavir is often part of combination therapy regimens, which may include other antiretroviral agents to improve treatment outcomes and reduce the risk of resistance.

Formula:C₃₇H₄₈N₄O₅

InChI:InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1

InChI key:InChIKey=KJHKTHWMRKYKJE-SUGCFTRWSA-N

SMILES:O=C1NCCCN1C(C(=O)NC(CC=2C=CC=CC2)CC(O)C(NC(=O)COC=3C(=CC=CC3C)C)CC=4C=CC=CC4)C(C)C

Synonyms:
A 157378.0
1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
(αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
1(2H)-Pyrimidineacetamide, N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, [1S-[1R*(R*),3R*,4R*]]-
ABT 378
ABT-378
UNII-2494G1JF75
Kaletra
(S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
See more synonyms
(1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
(2S)-N-[(2S,4S,5S)-5-{[(2,6-dimethylphenoxy)acetyl]amino}-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
1(2H)-Pyrimidineacetamide, N-((1S,3S,4S)-4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahyrdo-alpha-1-methylethyl)-2-oxo-, (alphaS)-
(alphaS)-Tetrahydro-N-((alphaS)-alpha-((2S,3S)-2-hydroxy-4-phenyl-3-(2-(2,6-xylyloxy)acetamido)butyl)phenethyl)-alpha-isopropyl-2-oxo-1(2H)-pyrimidineacetamide

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Product data	Purity	Price range	Estimated delivery
Lopinavir REF: 3B-L0377CAS: 192725-17-0	>98.0%(HPLC)	61.00 €~195.00 €	Fri 04 Apr 25
Lopinavir for system suitability CRS REF: 41-Y0001505CAS: 192725-17-0	- - -	115.00 €	Wed 09 Apr 25
Lopinavir for peak identification CRS REF: 41-Y0001506CAS: 192725-17-0	- - -	115.00 €	Wed 09 Apr 25
Lopinavir RS REF: 41-ICRS60025CAS: 192725-17-0	- - -	102.00 €	Wed 09 Apr 25
Lopinavir CRS REF: 41-Y0001498CAS: 192725-17-0	- - -	115.00 €	Wed 09 Apr 25
Lopinavir REF: 45-1370101CAS: 192725-17-0	- - -	1,516.00 €	Thu 10 Apr 25
(αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide REF: IN-DA003RD4CAS: 192725-17-0	%	To inquire	Fri 11 Apr 25
Lopinavir REF: 7W-GP6351CAS: 192725-17-0	≥ 98.0% (anhydrous basis)	22.00 €~156.00 €	Mon 14 Apr 25
Lopinavir REF: 54-OR1027378CAS: 192725-17-0	- - -	52.00 €~3,714.00 €	Mon 14 Apr 25
Lopinavir EP Impurity H REF: 4Z-L-3017CAS: 192725-17-0	- - -	To inquire	Mon 14 Apr 25
Lopinavir REF: 4Z-L-301CAS: 192725-17-0	- - -	To inquire	Mon 14 Apr 25
Lopinavir REF: 04-C14647200CAS: 192725-17-0	- - -	To inquire	Mon 14 Apr 25
Lopinavir, 98% REF: AC-45675CAS: 192725-17-0	98%	To inquire	Mon 14 Apr 25
Lopinavir REF: 86-MM1151.00CAS: 192725-17-0	- - -	1,500.00 €	Mon 14 Apr 25
Lopinavir REF: TM-T1623CAS: 192725-17-0	98% - 99.43%	48.00 €~188.00 €	Mon 21 Apr 25
Lopinavir REF: 10-F079428CAS: 192725-17-0	95.0%	To inquire	Mon 21 Apr 25
Lopinavir REF: TR-L469480CAS: 192725-17-0	- - -	118.00 €~209.00 €	Mon 21 Apr 25
Lopinavir - Bio-X ™ REF: 3D-BL164636CAS: 192725-17-0	Min. 98 Area-%	147.00 €	Tue 22 Apr 25
Lopinavir REF: 3D-FL16558CAS: 192725-17-0	Min. 97.5 Area-%	163.00 €~1,248.00 €	Tue 22 Apr 25
N5-Des[(2,6-dimethylphenoxy)acetyl] N5-Formal Lopinavir REF: TR-D288205CAS: 192725-17-0	- - -	11,848.00 €	Thu 22 May 25