CAS 1929583-17-4

5-Pyrimidinecarboxamide, 2-[[[2-(4-aminophenyl)-9-methyl-6-(4-morpholinyl)-9H-purin-8-yl]methyl]methylamino]-N-hydroxy-

Description:

5-Pyrimidinecarboxamide, 2-[[[2-(4-aminophenyl)-9-methyl-6-(4-morpholinyl)-9H-purin-8-yl]methyl]methylamino]-N-hydroxy- is a complex organic compound characterized by its multi-functional structure, which includes a pyrimidine carboxamide moiety and a purine derivative. This compound features a hydroxylamine group, which may contribute to its reactivity and potential biological activity. The presence of an aminophenyl group and a morpholine ring suggests that it may interact with biological targets, possibly influencing cellular processes. Its molecular structure indicates potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific pathways. The compound's CAS number, 1929583-17-4, allows for precise identification in chemical databases. As with many such compounds, its solubility, stability, and reactivity would depend on environmental conditions such as pH and temperature, and further studies would be necessary to elucidate its full biological profile and potential therapeutic uses.

Formula: C₂₃H₂₆N₁₀O₃

Synonyms:

• 5-Pyrimidinecarboxamide, 2-[[[2-(4-aminophenyl)-9-methyl-6-(4-morpholinyl)-9H-purin-8-yl]methyl]methylamino]-N-hydroxy-

Purinostat

CAS: 1929583-17-4

Purinostat is a selective inhibitor of HDACI/IIb with potential anti-leukemic properties. Its mesylate form, Purinostat mesylate, is effective at inhibiting the survival of Ph+ leukemic cells and CD34+ leukemic cells derived from CML patients. Purinostat mesylate targets HDACI/IIb, impacting several crucial factors for leukemia stem cell (LSC) survival, such as c-Myc, β-Catenin, E2f, Ezh2, Alox5, and mTOR. Additionally, Purinostat mesylate enhances glutamate metabolism in LSCs by increasing GLS1.

Formula: C₂₃H₂₆N₁₀O₃

Color and Shape: Solid

Molecular weight: 490.518

Ref: TM-T204269