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CAS 193153-04-7

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Otamixaban

Description:
Otamixaban is a synthetic small molecule that functions as a direct factor Xa inhibitor, primarily used in the context of anticoagulation therapy. It is characterized by its ability to selectively inhibit factor Xa, an essential enzyme in the coagulation cascade, thereby preventing thrombus formation. This compound is typically administered via intravenous routes and has been investigated for its potential in treating conditions such as acute coronary syndrome and during percutaneous coronary interventions. Otamixaban exhibits a relatively short half-life, which allows for rapid onset and offset of action, making it suitable for acute settings. Its pharmacokinetic profile includes high bioavailability and a predictable dose-response relationship, which are advantageous for clinical applications. Additionally, the safety profile of Otamixaban has been a focus of research, particularly concerning bleeding risks associated with anticoagulants. Overall, Otamixaban represents a significant advancement in anticoagulant therapy, offering a targeted approach to managing thrombotic disorders.
Formula:C25H26N4O4
InChI:InChI=1S/C25H26N4O4/c1-16(22(25(31)33-2)15-17-4-3-5-21(14-17)23(26)27)28-24(30)20-8-6-18(7-9-20)19-10-12-29(32)13-11-19/h3-14,16,22H,15H2,1-2H3,(H3,26,27)(H,28,30)/t16-,22-/m1/s1
InChI key:InChIKey=PFGVNLZDWRZPJW-OPAMFIHVSA-N
SMILES:C(N[C@@H]([C@@H](CC1=CC(C(=N)N)=CC=C1)C(OC)=O)C)(=O)C2=CC=C(C=C2)C=3C=CN(=O)=CC3
Synonyms:
  • Benzenepropanoic acid, 3-(aminoiminomethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]-, methyl ester, (αR)-
  • Benzenepropanoic acid, 3-(aminoiminomethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]-, methyl ester, [R-(R*,R*)]-
  • Fxv-673
  • Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate
  • Otamixaban
  • (αR)-3-(AMinoiMinoMethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester
  • [R-(R*,R*)]-3-(AMinoiMinoMethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester
  • methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate
  • OtaMixaban (FXV 673)
  • FXV 673; FXV673; FXV-673
  • See more synonyms
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Found 4 products.