CAS 193281-05-9

Pemetrexed Impurity 13

CAS: 193281-05-9

Formula: C₁₉H₂₁N₅O₇

Molecular weight: 431.41

Ref: 4Z-P-6814

LY 368962

Controlled Product

CAS: 193281-05-9

Applications LY 368962 is a metabolite of the antifolate Pemetrexed (P219500).
References Woodland, J.M. et al.: Drug Metab. Dispos., 25, 693 (1997);

Formula: C₁₉H₂₁N₅O₇

Color and Shape: Neat

Molecular weight: 431.40

Ref: TR-L486700

LY 368962

CAS: 193281-05-9

LY 368962 is a potent and selective activator of the metabotropic glutamate receptor subtype mGluR5. It has been shown to have no effect on other ion channels or on ligand-gated ion channels, such as nicotinic acetylcholine receptors and NMDA receptors. LY 368962 was used in a study that found it to be an effective inhibitor of the proliferation of human leukemia cells by blocking the interaction between two proteins, FKBP51 and eIF4E. The binding site for LY 368962 is located at the interface between these two proteins, preventing them from interacting with one another.

Formula: C₁₉H₂₁N₅O₇

Purity: Min. 95%

Molecular weight: 431.4 g/mol

Ref: 3D-THA28105