1H-Indazole-3,5-diamine, with the CAS number 19335-14-9, is an organic compound characterized by its indazole core, which consists of a five-membered ring containing two nitrogen atoms. This compound features amino groups (-NH2) at the 3 and 5 positions of the indazole ring, contributing to its reactivity and potential applications in medicinal chemistry. It is typically a solid at room temperature and may exhibit properties such as solubility in polar solvents, depending on the specific conditions. The presence of amino groups allows for hydrogen bonding and can influence the compound's interaction with biological targets, making it of interest in drug development. Additionally, 1H-Indazole-3,5-diamine may participate in various chemical reactions, including nucleophilic substitutions and coupling reactions, which are valuable in synthetic organic chemistry. Its structural characteristics and functional groups suggest potential applications in pharmaceuticals, particularly in the development of compounds targeting specific biological pathways.

1H-Indazole-3,5-diamine

19335-14-9: 1H-Indazole-3,5-diamine, with the CAS number 19335-14-9, is an organic compound characterized by its indazole core, which consists of a five-membered ring containing two nitrogen atoms. This compound features amino groups (-NH2) at the 3 and 5 positions of the indazole ring, contributing to its reactivity and potential applications in medicinal chemistry. It is typically a solid at room temperature and may exhibit properties such as solubility in polar solvents, depending on the specific conditions. The presence of amino groups allows for hydrogen bonding and can influence the compound's interaction with biological targets, making it of interest in drug development. Additionally, 1H-Indazole-3,5-diamine may participate in various chemical reactions, including nucleophilic substitutions and coupling reactions, which are valuable in synthetic organic chemistry. Its structural characteristics and functional groups suggest potential applications in pharmaceuticals, particularly in the development of compounds targeting specific biological pathways.

<p>1H-Indazole-3,5-diamine is a ligand that binds to the active site of the enzyme nitric oxide synthase. The binding of 1H-indazole-3,5-diamine inhibits the conversion of arginine to citrulline and disrupts the interaction between the enzyme and its cofactors. This leads to decreased production of nitric oxide. 1H-Indazole-3,5-diamine has been shown to cause cancer cell death in vitro by inhibiting DNA synthesis and increasing levels of reactive oxygen species. It also inhibits cancer cell growth in vivo by causing apoptosis and necrosis.</p>

CAS 19335-14-9

1H-Indazole-3,5-diamine

1H-Indazole-3,5-diamine

Ref: 3D-UAA33514