CAS 1935981-35-3

Formula: C19H18N4O4

InChI: InChI=1S/C19H18N4O4/c20-22-21-9-10-23(11-18(24)25)19(26)27-12-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,24,25)

InChI key: MLMPWBUAQAXGFT-UHFFFAOYSA-N

SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N(CCN=[N+]=[N-])CC(=O)O

N-(2-Azidoethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycine

CAS: 1935981-35-3

Formula: C₁₉H₁₈N₄O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 366.3706

Ref: IN-DA01V44X

2-[(2-Azidoethyl)[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid

CAS: 1935981-35-3

2-[(2-Azidoethyl)[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid

Formula: C₁₉H₁₈N₄O₄

Purity: 95%

Molecular weight: 366.38

Ref: 54-OR1065879

Fmoc-Aeg(N3)-OH

CAS: 1935981-35-3

2-[(2-Azidoethyl)[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid

Formula: C₁₉H₁₈N₄O₄

Purity: 95% (HPLC)

Molecular weight: 366.37

Ref: IN-DG00997310

Fmoc-Aeg(N3)-OH

CAS: 1935981-35-3

Fmoc-Aeg(N3)-OH is a click chemistry reagent characterized by its azide group that participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing alkyne groups. This building block, which also reacts in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN group-containing molecules, facilitates the alteration of cytotoxicity through the creation of peptidomimetics such as Cilengitide, Piscidin 1, and MC3, MC4, MC5 receptor agonists. Its incorporation in molecules can lead to conformational restraint in peptidic structures due to amidic nitrogen alkylation, which results in structures such as N-methylated peptides, allows backbone derivatization, and enables the design of macrocycles through intramolecular cross-linking or stabilization of the main chain by intramolecular cyclization. Fmoc-Aeg(N3)-OH is a potential cornerstone for the construction of custom peptide nucleic acids (PNAs) and peptide synthesis.

Formula: C₁₉H₁₈N₄O₄

Color and Shape: Solid

Molecular weight: 366.37

Ref: TM-T89827