CAS 193681-12-8

alamifovir

Description:

Alamifovir, with the CAS number 193681-12-8, is an antiviral compound that belongs to the class of nucleoside analogs. It is primarily investigated for its potential use in the treatment of viral infections, particularly HIV. The chemical structure of alamifovir features a modified nucleoside backbone, which allows it to interfere with viral replication by inhibiting reverse transcriptase, an essential enzyme for the life cycle of retroviruses. Alamifovir exhibits characteristics typical of nucleoside analogs, including the ability to mimic natural nucleotides, thereby incorporating into viral RNA or DNA and disrupting the synthesis process. Its pharmacological profile suggests a favorable bioavailability and a potential for oral administration. Research into alamifovir has focused on its efficacy, safety, and resistance patterns, as well as its role in combination therapies to enhance antiviral effectiveness. As with many antiviral agents, ongoing studies aim to elucidate its full therapeutic potential and optimize its use in clinical settings.

Formula: C₁₈H₁₈F₆N₅O₄PS

InChI: InChI=1/C18H18F6N5O4PS/c19-17(20,21)8-32-34(30,33-9-18(22,23)24)11-31-7-6-29-10-26-13-14(29)27-16(25)28-15(13)35-12-4-2-1-3-5-12/h1-5,10H,6-9,11H2,(H2,25,27,28)

SMILES: c1ccc(cc1)Sc1c2c([nH]c(=N)n1)n(CCOCP(=O)(OCC(F)(F)F)OCC(F)(F)F)cn2

Synonyms:

• Alamifovir [INN]
• Bis(2,2,2-trifluoroethyl) ((2-(2-amino-6-((4-methoxyphenyl)sulfanyl)-9H-purin-9-yl)ethoxy)methyl)phosphonate
• Ly 582563
• Ly582563
• Mcc 478
• Unii-0N739K2A8A
• Phosphonic acid, ((2-(2-amino-6-((4-methoxyphenyl)thio)-9H-purin-9-yl)ethoxy)methyl)-, bis(2,2,2-trifluoroethyl) ester
• bis(2,2,2-trifluoroethyl) ({2-[2-amino-6-(phenylsulfanyl)-9H-purin-9-yl]ethoxy}methyl)phosphonate
• Alamifovir

Alamifovir

CAS: 193681-12-8

Alamifovir is an antiviral agent, which is synthetically derived. The mode of action of Alamifovir involves the inhibition of viral replication within host cells by targeting specific viral enzymes crucial for the replication process. This interference with the viral life cycle diminishes the ability of the virus to propagate and spread within the host organism.

Formula: C₁₉H₂₀F₆N₅O₅PS

Purity: Min. 95%

Molecular weight: 575.42 g/mol

Ref: 3D-FA104025

Alamifovir

CAS: 193681-12-8

Alamifovir: HBV-specific antiviral, purine analog prodrug; active against wild-type/lamivudine-resistant HBV; inhibits DNA initiation/packaging.

Formula: C₁₉H₂₀F₆N₅O₅PS

Color and Shape: Solid

Molecular weight: 575.42

Ref: TM-T25023