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CAS 1937-89-9

:

Butoxamine

Description:
Butoxamine, with the CAS number 1937-89-9, is a chemical compound classified as a selective beta-2 adrenergic antagonist. It is primarily known for its role in pharmacological research, particularly in studies related to asthma and other respiratory conditions. Butoxamine exhibits a structure that includes a butoxy group, which contributes to its lipophilicity, allowing it to interact effectively with biological membranes. The compound is characterized by its ability to selectively inhibit beta-2 adrenergic receptors, which are involved in smooth muscle relaxation and bronchodilation. This selectivity makes it a valuable tool in understanding the mechanisms of beta-adrenergic signaling. However, butoxamine is not widely used in clinical practice due to the development of more effective and safer alternatives. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are important for researchers studying its potential therapeutic applications. Overall, butoxamine serves as a significant compound in the field of pharmacology, particularly in the context of adrenergic receptor research.
Formula:C15H25NO3
InChI:InChI=1/C15H25NO3/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6/h7-10,14,16-17H,1-6H3/t10-,14-/m0/s1
InChI key:InChIKey=TWUSDDMONZULSC-JEVNKCSWNA-N
SMILES:[C@H]([C@H](NC(C)(C)C)C)(O)C1=C(OC)C=CC(OC)=C1
Synonyms:
  • (1R,2S)-2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
  • (R*,S*)-(+-)-alpha-(1-((1,1-Dimethylethyl)amino)ethyl)-2,5-dimethoxybenzenemethanol
  • Benzenemethanol, alpha-((1R)-1-((1,1-dimethylethyl)amino)ethyl)-2,5-dimethoxy-, (alphaS)-rel-
  • Benzenemethanol, alpha-(1-((1,1-dimethylethyl)amino)ethyl)-2,5-dimethoxy-, (R*,S*)-(+-)-
  • Benzenemethanol, α-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]-2,5-dimethoxy-, (αS)-rel-
  • Benzenemethanol, α-[1-[(1,1-dimethylethyl)amino]ethyl]-2,5-dimethoxy-, (R*,S*)-
  • Benzyl alcohol, alpha-(1-(tert-butylamino)ethyl)-2,5-dimethoxy-, DL-erythro-
  • Benzyl alcohol, α-[1-(tert-butylamino)ethyl]-2,5-dimethoxy-, <span class="text-smallcaps">DL</span>-erythro-
  • Butaxamina [INN-Spanish]
  • Butaxamine
  • See more synonyms
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Found 1 products.
  • (+/-)-Butoxamine
    Biosynth
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    (+/-)-Butoxamine

    Controlled Product
    CAS:
    <p>Butoxamine is a 5-HT1A receptor agonist that has been shown to activate cardiac 2-adrenergic receptors. It also inhibits ATP-sensitive K+ channels in the heart, thereby inhibiting cardiac excitability and promoting relaxation. Butoxamine has been shown to have anticholinergic effects on the detrusor muscle of the bladder, as well as other effects on smooth muscle. The ester hydrochloride salt of butoxamine has been used in polymerase chain reaction (PCR) studies for its ability to bind single-stranded DNA templates. The drug also inhibits bacterial translocation by blocking bacterial DNA gyrase, an enzyme that maintains the integrity of bacterial DNA. Butoxamine is also a cyclase inhibitor, which prevents the production of cAMP from ATP. This inhibition leads to reduced levels of phosphodiesterase and may have anti-inflammatory effects.</p>
    Formula:C15H25NO3
    Purity:Min. 95%
    Molecular weight:267.36 g/mol

    Ref: 3D-FB158959

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