CAS 19388-87-5

Taurolidine

Description:

Taurolidine is a synthetic compound primarily known for its antimicrobial properties and is often used in medical applications, particularly in the field of surgery and infection control. It is a derivative of the amino acid taurine and is characterized by its ability to inhibit bacterial growth and biofilm formation, making it valuable in preventing infections associated with medical devices. Taurolidine exhibits low toxicity and is generally well-tolerated in clinical settings. Its mechanism of action involves the disruption of bacterial cell membranes and interference with metabolic processes. Additionally, taurolidine has been investigated for its potential anti-cancer properties, as it may induce apoptosis in certain cancer cell lines. The compound is typically administered in a solution form and can be used in various formulations, including topical applications and intravenous solutions. Overall, taurolidine's unique properties make it a significant substance in both antimicrobial therapy and potential cancer treatment strategies.

Formula: C₇H₁₆N₄O₄S₂

InChI: InChI=1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2

InChI key: InChIKey=AJKIRUJIDFJUKJ-UHFFFAOYSA-N

SMILES: C(N1CCS(=O)(=O)NC1)N2CCS(=O)(=O)NC2

Synonyms:

• 2H-1,2,4-Thiadiazine, 4,4′-methylenebis[tetrahydro-, 1,1,1′,1′-tetraoxide
• 4,4'-Methanediylbis(1,2,4-Thiadiazinane) 1,1,1',1'-Tetraoxide
• 4,4'-Methylenebis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide
• 4,4'-Methylenebis(perhydro-1,2,4-thiadiazine 1,1-dioxide)
• 4,4'-Methylenebis(tetrahydro-1,2,4-thiadiazine) 1,1,1',1'-tetraoxide
• 4,4′-Methylenebis(perhydro-1,2,4-thiadiazin 1,1-dioxide)
• Bis(1,1-dioxoperhydro-1,2,4-thiadiazin-4-yl)methane
• T 7329
• Taurolin
• Tauroline
• Taurolidine

4,4′-Methylenebis(perhydro-1,2,4-thiadiazin 1,1-dioxide)

CAS: 19388-87-5

Formula: C₇H₁₆N₄O₄S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 284.3563

Ref: IN-DA003UHO

4,4'-Methylenebis(1,2,4-Thiadiazinane 1,1-Dioxide)

CAS: 19388-87-5

4,4'-Methylenebis(1,2,4-Thiadiazinane 1,1-Dioxide)

Purity: 97%

Molecular weight: 284.36g/mol

Ref: 54-OR1028570

Taurolidine

CAS: 19388-87-5

Taurolidine

Purity: ≥95%

Molecular weight: 284.36g/mol

Ref: 54-BUP17019

Taurolidine

CAS: 19388-87-5

Formula: C₇H₁₆N₄O₄S₂

Color and Shape: White To Off-White Solid

Molecular weight: 284.35

Ref: 4Z-T-128001

Taurolidine

CAS: 19388-87-5

Formula: C₇H₁₆N₄O₄S₂

Purity: ≥ 97.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 284.4

Ref: 7W-GA2906

Taurolidine-d6

CAS: 19388-87-5

Formula: C₇H₁₀D₆N₄O₄S₂

Molecular weight: 290.39

Ref: 4Z-T-128006

Taurolidine

CAS: 19388-87-5

Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.

Formula: C₇H₁₆N₄O₄S₂

Purity: 99.79% - 99.81%

Color and Shape: Solid

Molecular weight: 284.36

Ref: TM-T7533

Taurolidine

Controlled Product

CAS: 19388-87-5

Applications Taurolidine is a derivative of the amino acid Taurine (T007850). Taurolidine exhibits antiendotoxin and antimicrobial activity, and has also been shown to exhibit antitumour activity in vitro and in vivo. Taurolidine is used for the treatment of sepsis and is utilized in hospitals to prevent catheter-related bloodstream infections.
References Jurewitsch, B., et al.: J. Parent. Enter. Nut., 22, 242 (1998); McCourt, M., et al.: Ann. Surg. Oncol., 7, 685 (2000); Willatts, S., et al.: Crit. Care Med., 23, 1033 (1995)

Formula: C₇H₁₆N₄O₄S₂

Color and Shape: Neat

Molecular weight: 284.36

Ref: TR-T009050

Taurolidine

Controlled Product

CAS: 19388-87-5

Taurine derivative; used to prevent infection in catheters

Formula: C₇H₁₆N₄O₄S₂

Color and Shape: White Powder

Molecular weight: 284.36 g/mol

Ref: 3D-FT15603

Taurolidin

CAS: 19388-87-5

Formula: C₇H₁₆N₄O₄S₂

Purity: 95.0%

Color and Shape: No data available.

Molecular weight: 284.35

Ref: 10-F462722

Taurolidine-D6

Controlled Product

CAS: 19388-87-5

Stability Unstable in Aqueous Solution
Applications Taurolidine-D6 is a labelled analogue of Taurolidine (T009050). Taurolidine is a derivative of the amino acid Taurine (T007850). Taurolidine exhibits antiendotoxin and antimicrobial activity, and has also been shown to exhibit antitumour activity in vitro and in vivo. Taurolidine is used for the treatment of sepsis and is utilized in hospitals to prevent catheter-related bloodstream infections.
References Jurewitsch, B., et al.: J. Parent. Enter. Nut., 22, 242 (1998); McCourt, M., et al.: Ann. Surg. Oncol., 7, 685 (2000); Willatts, S., et al.: Crit. Care Med., 23, 1033 (1995)

Formula: C₇D₆H₁₀N₄O₄S₂

Color and Shape: Neat

Molecular weight: 290.393

Ref: TR-T009052