CAS 19408-46-9: Kasugamycin hydrochloride

Description: Kasugamycin hydrochloride is an antibiotic compound primarily used in agriculture as a fungicide, particularly effective against certain plant pathogens. It is derived from the fermentation of the bacterium *Streptomyces kasugaensis*. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its application in various formulations. Kasugamycin functions by inhibiting protein synthesis in sensitive organisms, thereby preventing the growth of fungi. Its mode of action involves binding to the ribosomal RNA, disrupting the translation process. This compound is particularly noted for its effectiveness against diseases such as rice blast and other fungal infections in crops. While it is beneficial in agricultural practices, its use is regulated due to potential environmental impacts and the development of resistance in target organisms. Safety data sheets indicate that it should be handled with care, as it may pose health risks if ingested or inhaled. Overall, Kasugamycin hydrochloride is a significant tool in crop protection, contributing to agricultural productivity while necessitating responsible usage.

Formula: C₁₄H₂₅N₃O₉·ClH

InChI: InChI=1S/C14H25N3O9.ClH/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22;/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24);1H/t3-,4+,5+,6-,7+,8+,9-,10+,11+,14-;/m1./s1

InChI key: InChIKey=ZDRBJJNXJOSCLR-NZXABURVSA-N

SMILES: Cl.O=C(O)C(=N)NC1CC(N)C(OC1C)OC2C(O)C(O)C(O)C(O)C2O

Synonyms:

• (2R,3S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl 2-amino-4-{[(Z)-amino(carboxy)methylidene]amino}-2,3,4,6-tetradeoxy-alpha-D-arabino-hexopyranoside hydrochloride (1:1)
• 2,3,4,5,6-pentahydroxycyclohexyl 2-amino-4-{[(Z)-amino(carboxy)methylidene]amino}-2,3,4,6-tetradeoxyhexopyranoside
• <span class="text-smallcaps">D</smallcap>-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-arabino-hexopyranosyl]-, hydrochloride (1:1)
• <span class="text-smallcaps">D</smallcap>-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-arabino-hexopyranosyl]-, monohydrochloride
• Kasugamycin Hydrochloride Hydrate
• Kasugamycin hydrochloride
• Kasumin
• D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, monohydrochloride
• Kasugamycin, monohydrochloride
• D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, hydrochloride (1:1)

D-chiro-Inositol,3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-a-D-arabino-hexopyranosyl]-, monohydrochloride

CAS: 19408-46-9

• Formula: C₁₄H₂₆ClN₃O₉
• Purity: 90%
• Color and Shape: Solid
• Molecular weight: 415.8239

Kasugamycin hydrochloride

CAS: 19408-46-9

• Formula: C₁₄H₂₅N₃O₉·HCl
• Purity: ≥ 70.0%
• Color and Shape: White to almost white powder
• Molecular weight: 415.82

Kasugamycin hydrochloride

CAS: 19408-46-9

• Formula: C₁₄H₂₅N₃O₉·ClH
• Color and Shape: Neat
• Molecular weight: 415.82

Kasugamycin hydrochloride 100 µg/mL in Water

CAS: 19408-46-9

• Formula: C₁₄H₂₅N₃O₉·ClH
• Color and Shape: Single Solution
• Molecular weight: 415.82

Kasugamycin hydrochloride

CAS: 19408-46-9

Kasugamycin hydrochloride (Kasumin), an antibiotic from Streptomyces, discovered in 1965 by Hamao Umezawa, combats rice …

• Formula: C₁₄H₂₆ClN₃O₉
• Purity: 100% - 99.1%
• Color and Shape: Solid
• Molecular weight: 415.83

Kasugamycin Hydrochloride

CAS: 19408-46-9

Stability Hygroscopic Applications Kasugamycin Hydrochloride is an aminoglycoside antibiotic that inhibits the initiation of translation. …

• Formula: C₁₄H₂₅N₃O₉·ClH
• Color and Shape: Light Yellow To Beige
• Molecular weight: 415.82

Kasugamycin hydrochloride

CAS: 19408-46-9

Inhibitor of protein synthesis; aminoglycoside

• Formula: C₁₄H₂₅N₃O₉•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 415.82 g/mol