CAS 194154-40-0
:Cbz-Valine ganciclovir
Description:
Cbz-Valine ganciclovir, with the CAS number 194154-40-0, is a chemical compound that combines the antiviral properties of ganciclovir with a valine derivative protected by a carbobenzoxy (Cbz) group. This modification enhances the compound's stability and bioavailability. Ganciclovir itself is an acyclic nucleoside analog of guanosine, primarily used in the treatment of cytomegalovirus (CMV) infections, particularly in immunocompromised patients. The presence of the valine moiety may contribute to improved pharmacokinetic properties, potentially allowing for better cellular uptake and efficacy. Cbz-Valine ganciclovir is characterized by its ability to inhibit viral DNA synthesis, making it a valuable compound in antiviral therapy. Its structure typically includes a sugar moiety, a purine base, and the valine side chain, which can influence its interaction with viral enzymes. As with many pharmaceutical compounds, the specific characteristics such as solubility, stability, and reactivity can vary based on environmental conditions and formulation.
Formula:C22H28N6O7
Synonyms:- 2-(2-Amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-3-hydroxy-1-propyl N-(benzyloxycarbonyl)-L-valinate
- N-[(Phenylmethoxy)carbonyl]-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester
- Cbz-valganciclovir
- CBZ-L-Valganciclovir
- Cbz-Valineganciclovir
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Found 8 products.
Cbz-Valine ganciclovir
CAS:Formula:C22H28N6O7Purity:97%Color and Shape:SolidMolecular weight:488.49372-((2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl ((benzyloxy)carbonyl)-L-valinate
CAS:2-((2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl ((benzyloxy)carbonyl)-L-valinatePurity:97%Molecular weight:488.5g/molN-Carbobenzyloxy-L-valinyl-ganciclovir
CAS:Purity:(HPLC) ≥ 97.0%Color and Shape:White to off-white crystalline powderValganciclovir Impurity 9 (Mixture of Diastereomers)
CAS:Formula:C22H28N6O7Color and Shape:White To Off-White SolidMolecular weight:488.50N-Cbz-L-valinyl-ganciclovir
CAS:<p>N-Cbz-L-valinyl-ganciclovir is a prodrug of ganciclovir. It is synthesized by reacting the amino acid L-valine with the nucleoside analogue ganciclovir in an organic solvent. The product can be purified by filtration and crystallizing using hydrochloric acid and then recrystallized from a mixture of chloroform and trimethylsulfonium chloride. N-Cbz-L-valinyl-ganciclovir is more stable than ganciclovir, which has been shown to be degraded by urea hydrolase. This product can also be recycled after it has been used.</p>Formula:C22H28N6O7Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:488.49 g/molN-Carbobenzyloxy-L-valinyl-ganciclovir
CAS:Controlled Product<p>Applications N-Carbobenzyloxy-L-valinyl-ganciclovir (cas# 194154-40-0) is a compound useful in organic synthesis.<br></p>Formula:C22H28N6O7Color and Shape:NeatMolecular weight:488.49








