Description:Cbz-Valine ganciclovir, with the CAS number 194154-40-0, is a chemical compound that combines the antiviral properties of ganciclovir with a valine derivative protected by a carbobenzoxy (Cbz) group. This modification enhances the compound's stability and bioavailability. Ganciclovir itself is an acyclic nucleoside analog of guanosine, primarily used in the treatment of cytomegalovirus (CMV) infections, particularly in immunocompromised patients. The presence of the valine moiety may contribute to improved pharmacokinetic properties, potentially allowing for better cellular uptake and efficacy. Cbz-Valine ganciclovir is characterized by its ability to inhibit viral DNA synthesis, making it a valuable compound in antiviral therapy. Its structure typically includes a sugar moiety, a purine base, and the valine side chain, which can influence its interaction with viral enzymes. As with many pharmaceutical compounds, the specific characteristics such as solubility, stability, and reactivity can vary based on environmental conditions and formulation.
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