CAS: 194413-58-6 - Semaxanib

Formula: C₁₅H₁₄N₂O

InChI: InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-

InChI key: InChIKey=WUWDLXZGHZSWQZ-WQLSENKSSA-N

SMILES: O=C1NC=2C=CC=CC2C1=CC=3NC(=CC3C)C

Synonyms:

• (3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
• (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one
• (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
• (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one
• (Z)-Su 5416
• 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)-
• 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (Z)-
• 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone
• 3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)meth-(Z)-ylidene]-2-oxo-2,3-dihydroindole
• Nsc-696819
• Semaxanib
• Semoxind
• Su-5416
• Sugen
• Tsu-16

3-[(2,4-Dimethylpyrrol-5-yl)methylidenyl]-2-indolinon

CAS: 194413-58-6

• Formula: C₁₅H₁₄N₂O
• Purity: %
• Color and Shape: Solid
• Molecular weight: 238.2845

(Z)-Semaxinib

CAS: 194413-58-6

(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective …

• Formula: C₁₅H₁₄N₂O
• Purity: 96.09% - ≥95%
• Color and Shape: Solid
• Molecular weight: 238.28

Semaxanib (SU5416)

CAS: 194413-58-6

Semaxanib is a small molecule inhibitor of cell signaling pathways that has been shown to …

• Formula: C₁₅H₁₄N₂O
• Purity: Min. 95%
• Molecular weight: 238.28 g/mol