CAS 194413-58-6
:Semaxanib
Description:
Semaxanib, also known by its chemical name, is a small molecule that functions primarily as an angiogenesis inhibitor. It is characterized by its ability to interfere with the formation of new blood vessels, which is a critical process in tumor growth and metastasis. Semaxanib acts by targeting specific pathways involved in angiogenesis, particularly those related to vascular endothelial growth factor (VEGF). This compound is often studied in the context of cancer therapy, as inhibiting angiogenesis can potentially limit tumor progression and improve treatment outcomes. In terms of its chemical structure, Semaxanib features a unique arrangement of functional groups that contribute to its biological activity. The compound is typically administered in a controlled manner to maximize its therapeutic effects while minimizing side effects. Research continues to explore its efficacy and safety profile in various cancer types, making it a subject of interest in oncology and pharmacology.
Formula:C15H14N2O
InChI:InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-
InChI key:InChIKey=WUWDLXZGHZSWQZ-WQLSENKSSA-N
SMILES:C(=C\1/C=2C(NC1=O)=CC=CC2)\C=3NC(C)=CC3C
Synonyms:- (3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
- (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one
- (Z)-Su 5416
- 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)-
- 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (Z)-
- 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone
- 3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)meth-(Z)-ylidene]-2-oxo-2,3-dihydroindole
- Nsc-696819
- Semaxanib
- Semoxind
- Su-5416
- Sugen
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.
3-[(2,4-Dimethylpyrrol-5-yl)methylidenyl]-2-indolinon
CAS:Formula:C15H14N2OPurity:%Color and Shape:SolidMolecular weight:238.2845(Z)-3-((3,5-Dimethyl-1H-Pyrrol-2-Yl)Methylene)Indolin-2-One
CAS:<p>(Z)-3-((3,5-Dimethyl-1H-Pyrrol-2-Yl)Methylene)Indolin-2-One</p>Purity:99%Molecular weight:238.28g/mol(Z)-Semaxinib
CAS:<p>(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for</p>Formula:C15H14N2OPurity:98.82% - ≥95%Color and Shape:SolidMolecular weight:238.28


