CAS: 194423-06-8 - N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide

Formula: C₁₈H₁₃BrN₄O

InChI: InChI=1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3,5-11H,1H3,(H,22,24)(H,20,21,23)

InChI key: InChIKey=BTYYWOYVBXILOJ-UHFFFAOYSA-N

SMILES: O=C(C#CC)NC=1C=CC2=NC=NC(NC=3C=CC=C(Br)C3)=C2C1

Synonyms:

• N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide
• 2-Butynamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
• EKI 785
• CL 387785
• WAY-EKI 785

2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-

CAS: 194423-06-8

• Formula: C₁₈H₁₃BrN₄O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 381.2260

CL-387785

CAS: 194423-06-8

• Formula: C₁₈H₁₃BrN₄O
• Purity: >98.0%(GC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 381.23

CL-387785

CAS: 194423-06-8

CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.

• Formula: C₁₈H₁₃BrN₄O
• Purity: 96.68% - 98.09%
• Color and Shape: Solid
• Molecular weight: 381.23

CL 387785

CAS: 194423-06-8

Irreversible inhibitor of EGFR receptor

• Formula: C₁₈H₁₃BrN₄O
• Purity: Min. 95%
• Molecular weight: 381.23 g/mol

CL-387785 (EKI-785)

CAS: 194423-06-8

Applications CL-387785 (EKI-785) is an irreversible and selective EGFR inhibitor showing activity against mutations of …

• Formula: C₁₈H₁₃BrN₄O
• Color and Shape: Pale Yellow to Light Yellow Solid
• Molecular weight: 381.23