CAS 194785-18-7

6-CARBOXY-X-RHODAMINE

Description:

6-Carboxy-X-rhodamine, identified by its CAS number 194785-18-7, is a fluorescent dye commonly used in various biochemical and molecular biology applications. This compound is characterized by its vibrant fluorescence, which is typically in the orange-red spectrum, making it useful for labeling and tracking biomolecules in fluorescence microscopy and flow cytometry. The presence of a carboxylic acid group enhances its solubility in aqueous solutions and allows for conjugation with other molecules, facilitating its use in bioconjugation techniques. Additionally, 6-Carboxy-X-rhodamine exhibits good photostability, which is crucial for experiments requiring prolonged exposure to light. Its structural features include a rhodamine backbone, which contributes to its strong fluorescence properties. Overall, this dye is valued for its versatility in research applications, particularly in the fields of genetics, cell biology, and biochemistry, where it aids in the visualization and quantification of various biological processes.

Formula: C₃₃H₃₀N₂O₅

InChI: InChI=1/C33H30N2O5/c36-32(37)20-9-10-21(33(38)39)24(17-20)27-25-15-18-5-1-11-34-13-3-7-22(28(18)34)30(25)40-31-23-8-4-14-35-12-2-6-19(29(23)35)16-26(27)31/h9-10,15-17H,1-8,11-14H2,(H-,36,37,38,39)

SMILES: C1Cc2cc3c(c4cc(ccc4C(=O)[O-])C(=O)O)c4cc5CCCN6CCCc(c56)c4[o+]c3c3CCCN(C1)c23

Synonyms:

• 6-Rox
• 6-Carboxy-X-Rhodamine, For Fluorescence*
• 6-Carboxy-X-Rhodamine (Single Isomer)
• 4-carboxy-3-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium-9-yl)benzoate

6-Carboxy-X-rhodamine

CAS: 194785-18-7

Formula: C₃₃H₃₀N₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 534.6017

Ref: IN-DA00AP9L

6-ROX

CAS: 194785-18-7

6-ROX

Purity: ≥98%

Molecular weight: 534.6g/mol

Ref: 54-BUP09659

6-Carboxy-X-rhodamine

CAS: 194785-18-7

6-Carboxy-X-rhodamine

Purity: 98%

Color and Shape: Solid

Molecular weight: 534.60g/mol

Ref: 54-OR949700

6-Carboxy-X-rhodamine

CAS: 194785-18-7

Purity: ≥ 90.0%

Color and Shape: Dark powder

Molecular weight: 534.60

Ref: 7W-GT3614

6-ROX

CAS: 194785-18-7

6-ROX (6-Carboxy-X-rhodamine) is a fluorescent oligonucleotide marker and acts as an acceptor molecule coupled to 5-FAM as the donor in FRET imaging with

Formula: C₃₃H₃₀N₂O₅

Purity: 98.33%

Color and Shape: Solid

Molecular weight: 534.6

Ref: TM-T18903

6-Carboxy-X-rhodamine

CAS: 194785-18-7

Single isomer of 5(6)-ROX. It is a fluorescent dye used in RT-PCR methods as an internal reference to determine fluorescence variation that is not associated with the amplification process (plastic of the wells, small differences in concentration or volume, instrument measurements). It produces a constant fluorescence emission signal during the PCR process that is used to normalise the emission produced by the reporter. The fluorescence signal is compatible with most reporters. It is used to label the 5’ end of oligonucleotides as a reporter in the presence of a quencher at the 3’ end (dual labelled probe). During the amplification, the dye is cleaved, and the fluorescence increases proportionally with the amount of the specific sequence amplified during the PCR process. The development of the fluorescence signal is therefore specifically related to the amplification of the target sequence. 6-ROX with NHS-activated carboxylic acids reacts with primary amines.

Formula: C₃₃H₃₀N₂O₅

Purity: Min. 95%

Color and Shape: Red Powder

Molecular weight: 534.6 g/mol

Ref: 3D-FC72890

6-Carboxy-X-rhodamine

Controlled Product

CAS: 194785-18-7

Formula: C₃₃H₃₀N₂O₅

Color and Shape: Neat

Molecular weight: 451.52

Ref: TR-C183275