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CAS 1949840-87-2

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  • BCL-XL-IN-3

    CAS:
    <p>BCL-XL-IN-3 (Compound 11) is an inhibitor of BCL-XL, with a Ki of less than 0.01 nM. It suppresses cell viability in both normal Molt-4 cells and digitonin-permeabilized Molt-4 cells, with EC50 values of 77.8 nM and 0.07 nM, respectively. BCL-XL-IN-3 can be utilized as an ADC toxin for synthesizing Clezutoclax.</p>
    Formula:C46H55N7O6S
    Color and Shape:Solid
    Molecular weight:834.04