CAS 1950634-92-0

dBET6

CAS: 1950634-92-0

Formula: C₄₂H₄₅ClN₈O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 841.3741

Ref: IN-DA01EO5N

2-((S)-4-(4-Chlorophenyl)-2,3,9-Trimethyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepin-6-Yl)-N-(8-(2-((2-(2,6-Dioxopiperidin-3-Yl)-1,3-Dioxoisoindolin-4-Yl)Oxy)Acetamido)Octyl)Acetamide

CAS: 1950634-92-0

2-((S)-4-(4-Chlorophenyl)-2,3,9-Trimethyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepin-6-Yl)-N-(8-(2-((2-(2,6-Dioxopiperidin-3-Yl)-1,3-Dioxoisoindolin-4-Yl)Oxy)Acetamido)Octyl)Acetamide

Purity: 97%

Molecular weight: 841.37g/mol

Ref: 54-OR1024179

dBET6

CAS: 1950634-92-0

dBET6

Purity: ≥95%

Molecular weight: 841.37g/mol

Ref: 54-BUP15238

dBET6

CAS: 1950634-92-0

Formula: C₄₂H₄₅ClN₈O₇S

Molecular weight: 841.38

Ref: 4Z-K-031007

dBET6

CAS: 1950634-92-0

dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.

Formula: C₄₂H₄₅ClN₈O₇S

Purity: 97.57% - 99.12%

Color and Shape: Solid

Molecular weight: 841.37

Ref: TM-T5130

dBET6

CAS: 1950634-92-0

Purity: 98%

Molecular weight: 841.38

Ref: 10-F837796

dBET6

Controlled Product

CAS: 1950634-92-0

dBET6 is a heterobifunctional ubiquitin ligase that can both activate and deactivate proteins. It has been shown to have a role in leukemic stem cells, which are able to self-renew indefinitely. dBET6 binds to the bromodomain of the mcl-1 protein, which is involved in the regulation of apoptosis. dBET6 also binds to the cell factor molecule, which is present in cancer cells. The binding of dBET6 to these molecules leads to the activation or deactivation of specific cellular processes.

Formula: C₄₂H₄₅ClN₈O₇S

Purity: Min. 95%

Molecular weight: 841.38 g/mol

Ref: 3D-BD177448