CAS 1951408-58-4

MAK683

CAS: 1951408-58-4

MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).

Formula: C₂₀H₁₇FN₆O

Purity: 98.25% - 99.92%

Color and Shape: Solid

Molecular weight: 376.39

Ref: TM-T15201

MAK683

CAS: 1951408-58-4

MAK683

Purity: ≥98%

Molecular weight: 376.39g/mol

Ref: 54-BUP12500

MAK-683

CAS: 1951408-58-4

MAK-683 is a novel drug that inhibits protein lysine methylation. It is a Toll-like receptor modulator and structural biology agent that binds to the Toll-like receptor molecule and prevents it from binding to its target. MAK-683 has been shown to inhibit the activity of CDK4/6, which are enzymes that regulate the cell cycle. This drug also inhibits transcriptional regulation by interfering with the expression of inflammatory cytokines such as IL-1β, TNF-α, and IL-6. MAK-683 has been shown to be effective in treating cancer and chemoresistance, as well as inflammatory diseases like asthma.

Formula: C₂₀H₁₇FN₆O

Purity: Min. 95%

Molecular weight: 376.39 g/mol

Ref: 3D-BDD40858