CAS 195143-52-3

Argpyrimidine

Description:

Argpyrimidine, identified by its CAS number 195143-52-3, is a chemical compound that belongs to the class of pyrimidine derivatives. It is characterized by its unique structure, which includes a pyrimidine ring fused with an arginine-like moiety. This compound is notable for its potential biological activities, particularly in the context of oxidative stress and cellular signaling. Argpyrimidine is often studied for its role as a biomarker in various diseases, including diabetes and cardiovascular conditions, due to its formation from the reaction of arginine with reactive carbonyl species. Its properties include solubility in polar solvents and stability under physiological conditions, making it relevant for research in biochemistry and medicinal chemistry. The compound's interactions with proteins and its influence on cellular processes are areas of ongoing investigation, highlighting its significance in understanding disease mechanisms and developing therapeutic strategies.

Formula: C₁₁H₁₈N₄O₃

InChI: InChI=1S/C11H18N4O3/c1-6-9(16)7(2)15-11(14-6)13-5-3-4-8(12)10(17)18/h8,16H,3-5,12H2,1-2H3,(H,17,18)(H,13,14,15)/t8-/m0/s1

InChI key: InChIKey=DCPBQSFZQHFSMR-QMMMGPOBSA-N

SMILES: N(CCC[C@@H](C(O)=O)N)C=1N=C(C)C(O)=C(C)N1

Synonyms:

• N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine
• Argpyrimidine
• L-Ornithine, N5-(5-hydroxy-4,6-dimethyl-2-pyrimidinyl)-

N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine Hydrochloride Hydrate

Controlled Product

CAS: 195143-52-3

Applications N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine Hydrochloride Hydrate is an advanced glycation end-products with an antiglycation potential.
References Bhattacherjee, Abhishek, et al.: Inter. J. of Bio. Macromol., 102, 1274-1285 (2017)

Formula: C₁₁H₁₈N₄O₃·HCl·xH₂O

Color and Shape: Off-White

Molecular weight: 254.29 + 36.46 + x(18.02)

Ref: TR-H825805

N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine hydrochloride hydrate

CAS: 195143-52-3

N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine hydrochloride hydrate is a monoclonal antibody that is specific to lysine residues. It can be used in cancer tissue identification and detection of reactive cells. The formation rate of this antibody is dependent on the concentration of trifluoroacetic acid. N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine hydrochloride hydrate reacts with the amino group of lysine residues at pH 7.4 and has a logistic regression coefficient of 0.934 (95% confidence interval: 0.837 - 1.000). This antibody is also able to bind to pluripotent cells, which are cells capable of differentiating into any cell type, including neural cells in diabetic neuropathy patients and chaperones in biological samples.

Formula: C₁₁H₁₈N₄O₃

Purity: Min. 95%

Molecular weight: 254.29 g/mol

Ref: 3D-VHA14352