CAS 1952-15-4

4-Diphenylacetoxy-N-methylpiperidine methiodide

Description:

4-Diphenylacetoxy-N-methylpiperidine methiodide is a quaternary ammonium compound characterized by its structure, which includes a piperidine ring substituted with a methyl group and a diphenylacetoxy moiety. This compound is typically used in pharmacological research due to its potential as a muscarinic receptor antagonist. It is known for its ability to cross biological membranes, which is influenced by its quaternary ammonium nature, making it a subject of interest in studies related to neurotransmission and receptor interactions. The methiodide form indicates that the compound is a salt, which can enhance its solubility in polar solvents. In terms of physical properties, it is generally a white to off-white solid, and it may exhibit hygroscopic behavior. Safety data suggests that, like many quaternary ammonium compounds, it should be handled with care, as it may cause irritation upon contact with skin or eyes. Overall, 4-Diphenylacetoxy-N-methylpiperidine methiodide serves as a valuable tool in medicinal chemistry and pharmacology.

Formula: C₂₁H₂₆NO₂·I

InChI: InChI=1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1

InChI key: InChIKey=WWJHRSCUAQPFQO-UHFFFAOYSA-M

SMILES: C(C(OC1CC[N+](C)(C)CC1)=O)(C2=CC=CC=C2)C3=CC=CC=C3.[I-]

Synonyms:

• 1,1-Dimethyl-4-Diphenylacetoxypiperidinium Iodide
• 4-Benziloyloxy-N-methylpiperidine methiodide
• 4-Damp
• 4-Damp Methiodide
• 4-Damp Methiodide M3 Cholinergic Recept
• 4-Diphenylacetoxy-N-Methyl- Piperidine Methiodide 98+%
• 4-Diphenylacetyloxy-N-methylpiperidine methiodide
• 4-[(Diphenylacetyl)Oxy]-1,1-Dimethylpiperidinium
• 4-[(Diphenylacetyl)Oxy]-1,1-Dimethylpiperidinium Iodide
• N,N-Dimethyl-4-(diphenylacetoxy)piperidinium iodide
• Piperidinium, 4-[(2,2-diphenylacetyl)oxy]-1,1-dimethyl-, iodide (1:1)
• Piperidinium, 4-[(diphenylacetyl)oxy]-1,1-dimethyl-, iodide
• Piperidinium, 4-hydroxy-1,1-dimethyl-, iodide, diphenylacetate

4-DIPHENYLACETOXY-N-METHYLPIPERIDINE METHIODIDE

CAS: 1952-15-4

Formula: C₂₁H₂₆INO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 451.3411

Ref: IN-DA003LAR

4-DAMP

CAS: 1952-15-4

Formula: C₂₁H₂₆INO₂

Molecular weight: 451.40

Ref: 7W-GK4447

4-DAMP

CAS: 1952-15-4

4-DAMP

Purity: ≥95%

Molecular weight: 451.34g/mol

Ref: 54-BUP21740

4-DAMP

Controlled Product

CAS: 1952-15-4

Stability Hygroscopic
Applications 4-DAMP is a potent muscarinic M3 receptor antagonist.
References Teixeira-Neto, F. et al.: J. Vet. Pharmacol. Ther., 35, 313 (2012); White, C. et al.: J. Pharmacol. Exp. Ther., 339, 870 (2011)

Formula: C₂₁H₂₆INO₂

Color and Shape: Neat

Molecular weight: 451.34

Ref: TR-D136400

4-Damp

CAS: 1952-15-4

Formula: C₂₁H₂₆INO₂

Purity: 99.0%

Color and Shape: Solid

Molecular weight: 451.348

Ref: 10-F047163

4-DAMP-d3

Controlled Product

CAS: 1952-15-4

Formula: C₂₁H₂₃D₃NO₂I

Color and Shape: Neat

Molecular weight: 454.36

Ref: TR-D136402

4-DAMP

CAS: 1952-15-4

4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.

Formula: C₂₁H₂₆INO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 451.34

Ref: TM-T22511