CAS 195210-03-8

4-Trifluoromethylumbelliferyl-Alpha-D-N-acetylneuraminic Acid Sodium Salt

Controlled Product

CAS: 195210-03-8

Applications Used as a substrate in a fluorometric detection of poorly expressed natural and recombinant sialidases.
References Engstler, M., et al.: Anal. Biochem., 250, 176 (1997)

Formula: C₂₁H₂₁F₃NNaO₁₁

Color and Shape: Neat

Molecular weight: 543.38

Ref: TR-T792025

4-Trifluoromethylumbelliferyl a-D-N-acetylneuraminic acid

CAS: 195210-03-8

4-Trifluoromethylumbelliferyl a-D-N-acetylneuraminic acid is a fluorescent chemiluminescent substrate that is used in the detection of beta-galactosidase activity. Beta-galactosidase catalyzes the hydrolysis of 4-trifluoromethylumbelliferyl a-D-N-acetylneuraminic acid to form 4-trifluoromethylumbelliferone and D-galactose, which emits light at approximately 480 nm. This reaction can be detected by fluorescence spectrophotometry using a fluorometer or photometer. 4TFUNA is not toxic, does not inhibit enzymes, and has been tested for toxicity and mutagenicity using bacteria and mammalian cells.

Purity: Min. 95%

Molecular weight: 521.39 g/mol

Ref: 3D-ET04875