
CAS 195262-56-7
:GLP-2 (RAT)
Description:
GLP-2 (RAT), or Glucagon-Like Peptide-2, is a peptide hormone that plays a crucial role in the regulation of intestinal growth and function. It is derived from the proglucagon gene and is primarily secreted by the intestinal L-cells in response to nutrient intake. The CAS number 195262-56-7 specifically identifies the rat form of this peptide. GLP-2 is known for its ability to enhance intestinal mucosal growth, increase nutrient absorption, and promote the repair of the intestinal lining. It also has effects on gastric motility and can inhibit gastric acid secretion. The peptide is characterized by its relatively short half-life in circulation, necessitating careful consideration in therapeutic applications. Research into GLP-2 has implications for various gastrointestinal disorders, including inflammatory bowel disease and short bowel syndrome, highlighting its potential as a therapeutic agent. Overall, GLP-2 (RAT) is a significant molecule in the field of endocrinology and gastrointestinal physiology.
Formula:C166H256N44O56S1
Synonyms:- Glucagon-Like Peptide 2 (Rat)
- Glucagon-Like Peptide Ii Rat
- H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Thr-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Oh
- Hadgsfsdemntildnlatrdfinwliqtkitd
- Preproglucagon (146-178) (Rat)
- Proglucagon (126-158) (Rat)
- M.W. 3796.17 C166H256N44O56S
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Found 2 products.
GLP-2 (rat)
CAS:GLP-2 administration to mice or rats promotes stimulation of crypt cell proliferation and inhibition of enterocyte apoptosis resulting in hyperplasia of the small bowel villous epithelium. It also exerts trophic effects in animal models of both small and large bowel injury such as experimental small bowel resection or chemically induced colitis. In addition to stimulation of epithelial proliferation, GLP-2 also acutely regulates gastric emptying and exerts rapid metabolic effects promoting stimulation of intestinal hexose transport. The actions of GLP-2 are transduced via the GLP-2 receptor, a member of the glucagon-secretin G protein-coupled receptor superfamily.Formula:C166H256N44O56SPurity: 95.5%Color and Shape:WhiteMolecular weight:3796.19GLP-2(rat)
CAS:intestinal epithelium-specific growth factorFormula:C166H256N44O56SPurity:98%Color and Shape:SolidMolecular weight:3796.17

