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CAS 19542-51-9

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N-cbz-val-phe

Description:
N-Cbz-Val-Phe, also known as N-carbobenzyloxy-L-valyl-L-phenylalanine, is a dipeptide derivative characterized by the presence of a carbobenzyloxy (Cbz) protecting group on the amino group of valine. This compound features a valine and phenylalanine amino acid sequence, which contributes to its structural and functional properties. It is typically used in peptide synthesis and as an intermediate in the production of more complex peptides. The Cbz group serves as a protective moiety, allowing for selective reactions at other functional groups without interfering with the peptide backbone. N-Cbz-Val-Phe is generally stable under standard laboratory conditions but may undergo hydrolysis or deprotection under acidic or basic conditions. Its solubility is influenced by the presence of the Cbz group, which can enhance its solubility in organic solvents. This compound is of interest in medicinal chemistry and biochemistry for its potential applications in drug development and as a building block for peptide-based therapeutics.
Formula:C22H26N2O5
InChI:InChI=1/C22H26N2O5/c1-15(2)19(24-22(28)29-14-17-11-7-4-8-12-17)20(25)23-18(21(26)27)13-16-9-5-3-6-10-16/h3-12,15,18-19H,13-14H2,1-2H3,(H,23,25)(H,24,28)(H,26,27)/t18-,19-/m0/s1
SMILES:CC(C)[C@@H](C(=N[C@@H](Cc1ccccc1)C(=O)O)O)N=C(O)OCc1ccccc1
Synonyms:
  • Z-Val-Phe-OH
  • N-[(benzyloxy)carbonyl]-L-valyl-L-phenylalanine
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