CAS 1959551-27-9

5-[[1-[(3R)-4,4-Difluoro-3-(3-fluoro-1H-pyrazol-1-yl)-1-oxobutyl]-4-hydroxy-4-piperidinyl]methyl]-1-(4-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

Description:

The chemical substance with the name "5-[[1-[(3R)-4,4-Difluoro-3-(3-fluoro-1H-pyrazol-1-yl)-1-oxobutyl]-4-hydroxy-4-piperidinyl]methyl]-1-(4-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one" and CAS number "1959551-27-9" is a complex organic compound characterized by its multi-ring structure, which includes a pyrazolo[3,4-d]pyrimidine core. This compound features several functional groups, including a piperidine ring and multiple fluorine substituents, which may influence its biological activity and solubility. The presence of a hydroxy group suggests potential for hydrogen bonding, while the difluoro and fluoro groups may enhance lipophilicity and affect the compound's interaction with biological targets. Such structural characteristics often indicate potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific pathways or conditions. The compound's intricate structure and substituents suggest it may exhibit unique pharmacological properties, warranting further investigation in drug discovery and development contexts.

Formula: C₂₄H₂₃F₄N₇O₃

InChI: InChI=1S/C24H23F4N7O3/c25-15-1-3-16(4-2-15)35-22-17(12-30-35)23(37)33(14-29-22)13-24(38)6-9-32(10-7-24)20(36)11-18(21(27)28)34-8-5-19(26)31-34/h1-5,8,12,14,18,21,38H,6-7,9-11,13H2/t18-/m1/s1

InChI key: InChIKey=BLSNYSFLZAWBIV-GOSISDBHSA-N

SMILES: O=C1C2=C(N(N=C2)C3=CC=C(F)C=C3)N=CN1CC4(O)CCN(C(C[C@H](C(F)F)N5N=C(F)C=C5)=O)CC4

Synonyms:

• 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 5-[[1-[(3R)-4,4-difluoro-3-(3-fluoro-1H-pyrazol-1-yl)-1-oxobutyl]-4-hydroxy-4-piperidinyl]methyl]-1-(4-fluorophenyl)-1,5-dihydro-
• 5-[[1-[(3R)-4,4-Difluoro-3-(3-fluoro-1H-pyrazol-1-yl)-1-oxobutyl]-4-hydroxy-4-piperidinyl]methyl]-1-(4-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
• (R)-FT671

(R)-FT671

CAS: 1959551-27-9

(R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective inhibitor of USP7 (IC50 of 52 nM)

Formula: C₂₄H₂₃F₄N₇O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 533.48

Ref: TM-T12621

(R)-FT671

CAS: 1959551-27-9

FT671 is an antibody that binds to the extracellular domain of the human angiotensin II type 1 receptor. It has been shown to inhibit the binding of angiotensin II to its receptor and block the activation of signaling pathways in cells. FT671 can be used as a research tool for studying peptides, cell biology, pharmacology, protein interactions, and ion channels. The antibody is also a ligand that can activate receptors by binding to them.

Formula: C₂₄H₂₃F₄N₇O₃

Purity: Min. 95%

Molecular weight: 533.5 g/mol

Ref: 3D-JDD55127