CAS 19608-29-8
:21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
Description:
21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione, with the CAS number 19608-29-8, is a synthetic steroid compound that belongs to the class of corticosteroids. It features a pregnane backbone, characterized by a steroid structure with a hydroxyl group at the 21-position and an oxopropoxy group at the 17-position. This compound exhibits anti-inflammatory and immunosuppressive properties, making it relevant in therapeutic applications, particularly in the treatment of various inflammatory conditions and autoimmune disorders. Its structural modifications enhance its pharmacological activity compared to natural corticosteroids. The presence of the ketone and hydroxyl functional groups contributes to its reactivity and solubility in organic solvents. As with many steroid derivatives, it may also interact with specific receptors in the body, influencing gene expression and metabolic processes. Safety and efficacy profiles are essential for its use in clinical settings, and it is typically administered under medical supervision to mitigate potential side effects associated with steroid use.
Formula:C24H34O5
InChI:InChI=1S/C24H34O5/c1-4-21(28)29-24(20(27)14-25)12-9-19-17-6-5-15-13-16(26)7-10-22(15,2)18(17)8-11-23(19,24)3/h13,17-19,25H,4-12,14H2,1-3H3/t17-,18+,19+,22+,23+,24+/m1/s1
InChI key:InChIKey=GPNHMOZDMYNCPO-PDUMRIMRSA-N
SMILES:O(C(CC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](CC1)([C@]3([C@](CC2)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])[H]
Synonyms:- 17Alpha-Propionate
- 21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
- Clascoterone
- Pregn-4-ene-3,20-dione, 17,21-dihydroxy-, 17-propionate
- Pregn-4-ene-3,20-dione, 21-hydroxy-17-(1-oxopropoxy)-
- Winlevi
- CB-03-01
- CB-03-01 17alpha-propionate
- Cortexolone-17a-propionate D6 major
- CB-03-01;CORTEXOLONE 17Α-PROPIONATE;CORTEXOLONE 17 ALPHA-PROPIONATE
- Cortexolone 17-alpha-propionate
- (8R,9S,10R,13S,14S,17R)-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate
- 17 alpha-propionate (CB-03-01)
- 17alpha-propio17-(1-oxopropoxy)pregn-4-ene-3,20-dione
- Cortexolone 17α-propionate
- Cortexolone 17-α-propionate
- See more synonyms
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Found 9 products.
Cortexolone 17α-propionate
CAS:Formula:C24H34O5Purity:99%Color and Shape:SolidMolecular weight:402.5238Clascoterone
CAS:<p>Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.</p>Formula:C24H34O5Purity:99.2% - 99.64%Color and Shape:SolidMolecular weight:402.52Clascoterone
CAS:Controlled Product<p>Clascoterone is a topical antiandrogen, which is a synthetic steroidal product with mechanisms focused on inhibiting androgen receptors. Derived from a modified steroid structure, this compound exhibits a targeted approach to addressing conditions influenced by androgen activity, particularly in cutaneous applications. The mode of action of Clascoterone involves competitive inhibition at the androgen receptor sites, thereby reducing the impact of dihydrotestosterone, which plays a significant role in the pathophysiology of acne.</p>Formula:C24H34O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:402.52 g/molClascoterone - Bio-X ™
CAS:Controlled Product<p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formula:C24H34O5Purity:Min. 95%Color and Shape:PowderMolecular weight:402.52 g/molClascoterone
CAS:Controlled Product<p>Applications Clascoterone is being developed as a topical cream by Cassiopea for androgen-dependent skin disorders.<br>References Dhillon, S., et al.: Drugs, 80, 1745 (2020)<br></p>Formula:C24H34O5Color and Shape:NeatMolecular weight:402.5238
