CAS 1962160-86-6

Fmoc-Thr(tBu)-Pen-OH

Description:

Fmoc-Thr(tBu)-Pen-OH is a chemical compound commonly used in peptide synthesis and research. It features a protected form of the amino acid threonine, where the hydroxyl group is protected by a fluorenylmethyloxycarbonyl (Fmoc) group, and the side chain is further protected by a tert-butyl (tBu) group. The "Pen" in the name indicates the presence of a penicillamine moiety, which can influence the compound's reactivity and properties. This compound is typically utilized in solid-phase peptide synthesis due to its stability and ease of handling. Its structure allows for selective deprotection under mild conditions, facilitating the stepwise assembly of peptides. The presence of the Fmoc group provides a convenient method for monitoring the synthesis process through UV absorbance. Additionally, the tert-butyl protection enhances solubility and stability during synthesis. Overall, Fmoc-Thr(tBu)-Pen-OH is a valuable building block in the field of medicinal chemistry and peptide research, contributing to the development of various bioactive compounds.

Formula: C₃₂H₃₆N₂O₆

Synonyms:

• (2S)-2-[(2S,3R)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-phenylpropanoic acid
• Fmoc-Thr(tBu)-Pen-OH
• Fmoc-Thr(tBu)-Phe-OH
• (2S)-2-[(2S,3R)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-phenylpropanoic acid
• (N-Fmoc-O-tert-butyl-L-threoninyl)-L-phenylalanine

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine

CAS: 1962160-86-6

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine

Purity: 98%

Molecular weight: 544.65g/mol

Ref: 54-OR1067491