CAS 196413-73-7

(CYS(ET)2,7)-ALPHA-CGRP (HUMAN)

Description:

(CYS(ET)2,7)-ALPHA-CGRP (HUMAN), with the CAS number 196413-73-7, is a synthetic peptide that is a modified form of the human calcitonin gene-related peptide (CGRP). This peptide is characterized by the substitution of cysteine residues, which enhances its stability and bioactivity. CGRP is known for its role in vasodilation and is involved in various physiological processes, including pain transmission and neurogenic inflammation. The modification with ethyl groups at specific positions (CYS(ET)2,7) is intended to improve its pharmacokinetic properties, such as solubility and resistance to enzymatic degradation. This peptide is of interest in research related to migraine treatment and other neurological conditions due to its potent vasodilatory effects and involvement in the central nervous system. Its structure and modifications make it a valuable tool for studying CGRP's biological functions and potential therapeutic applications.

Synonyms:

• Ala-Cys(Et)-Asp-Thr-Ala-Thr-Cys(Et)-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-Nh2
• H-Ala-Cys(Et)-Asp-Thr-Ala-Thr-Cys(Et)-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-Nh2
• (Cys(Et)2,7)-Alpha-Calcitonin Gene-Related Peptide (Human)

(Cys(Et)2·7)-a-CGRP (human) trifluoroacetate salt

CAS: 196413-73-7

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Formula: C₁₆₇H₂₇₇N₅₁O₄₉S₂

Purity: Min. 95%

Molecular weight: 3,847.43 g/mol

Ref: 3D-FC109613