CAS 1964490-09-2

L-Ornithinamide, N-[31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,29-dioxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacont-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

Description:

L-Ornithinamide, N-[31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,29-dioxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacont-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups and a long carbon chain. This compound features an ornithine derivative, suggesting potential biological activity, particularly in the context of amino acid metabolism or peptide synthesis. The presence of dioxo and oxo functional groups indicates potential reactivity, while the nitrophenoxy moiety may contribute to its solubility and interaction with biological systems. The compound's large size and multiple heteroatoms suggest it may exhibit unique properties, such as specific binding affinities or enhanced stability in certain environments. Its CAS number, 1964490-09-2, allows for precise identification in chemical databases, facilitating research and application in fields such as medicinal chemistry or biochemistry. Overall, this compound's structural complexity hints at potential utility in pharmaceutical development or as a biochemical probe.

Formula: C₅₁H₇₄N₈O₂₀

Synonyms:

• Mal-amide-PEG8-Val-Cit-PAB-PNP
• L-Ornithinamide, N-[31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,29-dioxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacont-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

Mal-amide-PEG8-Val-Cit-PAB-PNP

CAS: 1964490-09-2

Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker comprising a maleimide group, a PEG spacer, a Val-Cit dipeptide, PAB, and a PNP carbonate. The maleimide serves as a thiol-specific covalent connector for labeling cysteine residues in proteins, whereas the PNP group acts as a highly reactive leaving group. The Val-Cit linker is cleaved by cytoplasmic peptidases.

Formula: C₅₁H₇₄N₈O₂₀

Color and Shape: Solid

Molecular weight: 1119.18

Ref: TM-TYD-01921