CAS 19666-76-3

Panaxadiol

Description:

Panaxadiol is a triterpenoid saponin primarily derived from ginseng, particularly from the roots of Panax ginseng. It is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and immunomodulatory effects. Structurally, Panaxadiol features a dammarane skeleton, which is characteristic of many ginsenosides, contributing to its biological activity. The compound is often studied for its role in traditional medicine and its potential therapeutic applications, including enhancing physical performance and cognitive function. Panaxadiol is typically found in various formulations, including herbal supplements and extracts, and is recognized for its ability to interact with various biological pathways. Its safety profile and efficacy are subjects of ongoing research, particularly in the context of its use in complementary and alternative medicine. As with many natural products, the specific effects and mechanisms of action of Panaxadiol can vary based on dosage, formulation, and individual response.

Formula: C₃₀H₅₂O₃

InChI: InChI=1/C30H52O3/c1-25(2)13-9-14-30(8,33-25)19-10-16-29(7)24(19)20(31)18-22-27(5)15-12-23(32)26(3,4)21(27)11-17-28(22,29)6/h19-24,31-32H,9-18H2,1-8H3

SMILES: CC1(C)CCCC(C)(C2CCC3(C)C2C(CC2C4(C)CCC(C(C)(C)C4CCC32C)O)O)O1

Synonyms:

• Dammarane-3Beta,12Beta-Diol
• Panaxadiol 98.0% By Hplc
• (3beta,12beta,20R)-20,25-epoxydammarane-3,12-diol
• 20,25-Epoxydammarane-3,12-Diol

Panaxadiol

CAS: 19666-76-3

Panaxadiol

Purity: ≥98%

Molecular weight: 460.73g/mol

Ref: 54-BUP15993

Panaxadiol

CAS: 19666-76-3

Formula: C₃₀H₅₂O₃

Molecular weight: 460.74

Ref: 7W-GY0157

Panaxadiol

CAS: 19666-76-3

Panaxadiol , a ginseng saponin with a dammarane skeleton, selectively interferes with the cell cycle in human cancer cell lines, it inhibits DNA synthesis in a dose-dependent manner with IC50 values ranging from 0.8 to 1.2 μM in SK-HEP-1 cells and HeLa cells, it selectively elevates p21WAF1/CIP1 levels and thereby arrests the cell cycle at G1/S phase by down-regulating Cyclin A–Cdk2 activity.

Formula: C₃₀H₅₂O₃

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 460.743

Ref: BP-BP1060

Panaxadiol

CAS: 19666-76-3

Formula: C₃₀H₅₂O₃

Purity: >95.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 460.74

Ref: 3B-P2811

Panaxadiol

CAS: 19666-76-3

Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.

Formula: C₃₀H₅₂O₃

Purity: 98% - 99.9%

Color and Shape: Solid

Molecular weight: 460.73

Ref: TM-T2763

Panaxadiol

CAS: 19666-76-3

Oxygen-heterocyclic compound

Formula: C₃₀H₅₂O₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 460.74

Ref: 5G-89750

Panaxadiol

Controlled Product

CAS: 19666-76-3

Panaxadiol is a bioactive compound, classified as a dammarane-type tetracyclic triterpenoid, which is derived from ginseng, specifically from the plant species Panax ginseng. Its structure and chemical properties are extracted and isolated from the roots of this medicinal plant using advanced phytochemical methods.

Formula: C₃₀H₅₂O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 460.73 g/mol

Ref: 3D-FP09976

Panaxadiol

Controlled Product

CAS: 19666-76-3

Applications Panaxadiol is the purified sapogenin of ginseng saponins, which exhibits anti-tumor activity. Research has shown Panaxadiol exhibited enhancing activity towards human colorectal cancer cells.
References Li, X.L., et al.: Cancer. Chemotherap. Pharmacol., 64, 1097 (2009); Jung, H.K., et al.: J, Ginseng. Res., 33, 26 (2009);

Formula: C₃₀H₅₂O₃

Color and Shape: Neat

Molecular weight: 460.73

Ref: TR-P193255

Dammarane-3,12-diol, 20,25-epoxy-, (3b,12b,20R)-

CAS: 19666-76-3

Formula: C₃₀H₅₂O₃

Color and Shape: Solid

Molecular weight: 460.7321

Ref: IN-DA00I3KV