CAS 196808-45-4

Farglitazar

Description:

Farglitazar is a synthetic compound that belongs to the class of thiazolidinediones, which are primarily known for their role as insulin sensitizers in the treatment of type 2 diabetes. It acts as a dual agonist for peroxisome proliferator-activated receptors (PPARs), specifically PPAR-γ and PPAR-α, which are involved in the regulation of glucose and lipid metabolism. This dual activity can enhance insulin sensitivity and improve lipid profiles, making it a candidate for managing metabolic disorders. Farglitazar has been studied for its potential effects on reducing blood glucose levels and improving overall metabolic health. However, like other thiazolidinediones, it may be associated with side effects such as weight gain and fluid retention. Its chemical structure includes a thiazolidine ring, which is characteristic of its class, and it exhibits specific physicochemical properties that influence its bioavailability and pharmacokinetics. As with any pharmaceutical compound, ongoing research is essential to fully understand its efficacy and safety profile in clinical settings.

Formula: C₃₄H₃₀N₂O₅

InChI: InChI=1S/C34H30N2O5/c1-23-29(36-33(41-23)26-12-6-3-7-13-26)20-21-40-27-18-16-24(17-19-27)22-31(34(38)39)35-30-15-9-8-14-28(30)32(37)25-10-4-2-5-11-25/h2-19,31,35H,20-22H2,1H3,(H,38,39)/t31-/m0/s1

InChI key: InChIKey=ZZCHHVUQYRMYLW-HKBQPEDESA-N

SMILES: C(=O)(C1=C(N[C@@H](CC2=CC=C(OCCC=3N=C(OC3C)C4=CC=CC=C4)C=C2)C(O)=O)C=CC=C1)C5=CC=CC=C5

Synonyms:

• <span class="text-smallcaps">L</span>-Tyrosine, N-(2-benzoylphenyl)-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-
• Farglitazar
• G1 262570
• Gi 262570X
• Gi-262570
• N-(2-Benzoylphenyl)-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-<span class="text-smallcaps">L</span>-tyrosine
• N-(2-Benzoylphenyl)-O-[4-[2-(5-methyl-2-phenyloxazol-4-yl)ethyl]-L-tyrosine
• N-(2-benzoylphenyl)-O-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]-L-tyrosine
• N-(2-Benzoylphenyl)-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-L-tyrosine
• L-Tyrosine, N-(2-benzoylphenyl)-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-

Farglitazar

CAS: 196808-45-4

Farglitazar

Purity: ≥98%

Molecular weight: 546.61g/mol

Ref: 54-BUP01001

N-(2-Benzoylphenyl)-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-L-tyrosine

Controlled Product

CAS: 196808-45-4

Formula: C₃₄H₃₀N₂O₅

Color and Shape: Neat

Molecular weight: 546.612

Ref: TR-F102370

Farglitazar

CAS: 196808-45-4

Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.

Formula: C₃₄H₃₀N₂O₅

Purity: 99.4% - 99.52%

Color and Shape: Solid

Molecular weight: 546.61

Ref: TM-T27303