CAS 19690-23-4

2-Amino-6-iodopurine

Description:

2-Amino-6-iodopurine is a purine derivative characterized by the presence of an amino group at the 2-position and an iodine atom at the 6-position of the purine ring. This compound is typically a white to off-white crystalline solid, and it is soluble in polar solvents such as water and alcohols, which facilitates its use in various biochemical applications. The presence of the amino group contributes to its basicity, while the iodine atom can enhance its reactivity and potential for substitution reactions. 2-Amino-6-iodopurine is often utilized in nucleic acid research and as a building block in the synthesis of nucleoside analogs, which can have implications in antiviral and anticancer therapies. Its molecular structure allows it to participate in hydrogen bonding, making it relevant in studies of molecular interactions and enzyme mechanisms. As with many chemical substances, proper handling and safety precautions are essential due to its potential biological activity and reactivity.

Formula: C₅H₄IN₅

InChI: InChI=1/C5H4IN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)

SMILES: c1nc2c(I)[nH]c(=N)[nH]c2n1

Synonyms:

• 2-Amino-6-iodo-7H-purine
• 2-Amino-6-Iodo
• 6-Iodo-7H-Purin-2-Amine
• 9H-Purin-2-amine, 6-iodo-
• 6-Iodoguanine
• 6-iodo-5H-purin-2-amine
• 2-Amino-6-iodo purine

2-Amino-6-iodopurine

CAS: 19690-23-4

Formula: C₅H₄IN₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystalline

Molecular weight: 261.03

Ref: 3B-A2068

6-Iodo-9H-purin-2-amine

CAS: 19690-23-4

Formula: C₅H₄IN₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 261.0232

Ref: IN-DA003N8Z

2-Amino-6-iodo-7H-purine

CAS: 19690-23-4

2-Amino-6-iodo-7H-purine

Purity: 99%

Color and Shape: Powder

Molecular weight: 261.02g/mol

Ref: 54-OR3725

2-Amino-6-iodopurine

CAS: 19690-23-4

2-Amino-6-iodopurine is an analog of the purine nucleoside guanine, which has been used to synthesize a variety of boronic acids. The most common use for 2-amino-6-iodopurine is in the synthesis of benzylboronic acid, which can be used as an organometallic reagent in organic synthesis. This compound also has dehydrogenase activity and has been shown to catalyze the conversion of benzoic acid to benzaldehyde, mediated by NADH. 2-Amino-6-iodopurine is found in the biosynthesis of ribonucleotides and deoxyribonucleotides, where it reacts with chloride ions and phosphate groups to form adenylate and xanthosine monophosphates.

Formula: C₅H₄IN₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 261.02 g/mol

Ref: 3D-FA08193

6-Iodo-7H-purin-2-amine

CAS: 19690-23-4

Formula: C₅H₄IN₅

Purity: 99%(HPLC);RG

Molecular weight: 261.026

Ref: 10-F065032

2-Amino-6-iodopurine

Controlled Product

CAS: 19690-23-4

Applications 2-Amino-6-iodopurine is used as a reagent in the synthesis of Lobucavir (L469360) which is an antiviral agent.
References Singh, J., et al.: Org. Process Res. Dev., 2, 393 (1998);

Formula: C₅H₄IN₅

Color and Shape: Neat

Molecular weight: 261.02

Ref: TR-A611721