CAS 197387-33-0

Cyclohexanone, 4-(bromomethyl)-

Description:

Cyclohexanone, 4-(bromomethyl)- is an organic compound characterized by a cyclohexanone ring with a bromomethyl group attached to the fourth carbon. It is a colorless to pale yellow liquid with a distinctive odor, typical of ketones. The presence of the bromomethyl group introduces reactivity, making it a useful intermediate in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. This compound is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic cyclohexane structure. Its chemical properties include the ability to undergo nucleophilic substitution reactions due to the electrophilic nature of the bromine atom. Additionally, cyclohexanone derivatives are known for their applications in the production of polymers and as solvents. Safety considerations should be taken into account, as it may pose health risks if inhaled or ingested, and appropriate handling procedures should be followed to minimize exposure.

Formula: C₇H₁₁BrO

Synonyms:

• 4-(bromomethyl)cyclohexanone
• Cyclohexanone, 4-(bromomethyl)-
• 4-(bromomethyl)cyclohexan-1-one

Cyclohexanone, 4-(bromomethyl)-

CAS: 197387-33-0

Formula: C₇H₁₁BrO

Purity: 96%

Color and Shape: Solid

Molecular weight: 191.0656

Ref: IN-DA002AS5

4-(Bromomethyl)cyclohexan-1-one

CAS: 197387-33-0

4-(Bromomethyl)cyclohexan-1-one

Purity: 96%

Molecular weight: 191.07g/mol

Ref: 54-OR88035

4-(Bromomethyl)cyclohexan-1-one

CAS: 197387-33-0

Purity: 96%

Color and Shape: Solid

Molecular weight: 191.0679932

Ref: 10-F621538

4-(Bromomethyl)cyclohexan-1-one

CAS: 197387-33-0

The bis-Grignard reagent, also known as a bifunctional organometallic compound, is an organic chemistry reactive intermediate used in the synthesis of diverse organic molecules. This type of reagent is prepared by the reaction of a magnesium halide with an alkyl or aryl halide. The Grignard reagent reacts with electrophiles to form carbon-carbon bonds. The catellani reaction is an example of this type of reaction. A new method for the efficient synthesis of 4-(bromomethyl)cyclohexan-1-one has been developed using a cross-coupling strategy and a phosphine ligand. This process begins with the formation of a palladium catalyst via oxidative addition, followed by nucleophilic displacement with methyl iodide to give 4-(bromomethyl)cyclohexan-1-one in high yield and excellent purity.

Formula: C₇H₁₁BrO

Purity: Min. 95%

Molecular weight: 191.07 g/mol

Ref: 3D-XHA38733