CAS 19741-14-1

4-(N-(2,4-diamino-6-pteridinylme)-N-me-amino)benz

Description:

The chemical substance known as "4-(N-(2,4-diamino-6-pteridinylmethyl)-N-methylamino)benz" with the CAS number 19741-14-1 is a synthetic compound that belongs to the class of pteridine derivatives. It features a pteridine ring system, which is a bicyclic structure containing nitrogen atoms, contributing to its biological activity. The presence of amino groups in its structure suggests potential interactions with biological targets, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. This compound may exhibit properties such as solubility in polar solvents, and its reactivity can be influenced by the functional groups attached to the pteridine and benzene moieties. Additionally, its molecular structure may allow for hydrogen bonding and other intermolecular interactions, which can affect its pharmacokinetics and pharmacodynamics. Overall, the characteristics of this compound make it a subject of study for its potential therapeutic applications, particularly in the fields of oncology and antimicrobial research.

Formula: C₁₅H₁₅N₇O₂

InChI: InChI=1/C15H15N7O2/c1-22(10-4-2-8(3-5-10)14(23)24)7-9-6-18-13-11(19-9)12(16)20-15(17)21-13/h2-6H,7H2,1H3,(H,23,24)(H4,16,17,18,20,21)

SMILES: CN(Cc1cnc2c(c(N)[nH]c(=N)n2)n1)c1ccc(cc1)C(=O)O

Synonyms:

• 4-(N-(2,4-diamino-6-pteridinyl-*methyl)-N-methyl-
• 4-(N-(2,4-diamino-6-pteridinylmethyl)*-N-methyl-
• Bis(4-((2,4-Diaminopteridin-6-Ylmethyl)Methylamino)Benzoic) Acid Hydrochloride Tetrahydrate
• 4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino]benzoic acid hemihydrochloride dihydrate
• 4-{[(2,4-Diaminopteridin-6-Yl)Methyl](Methyl)Amino}Benzoic Acid

METHOTREXATE IMPURITY E CRS

CAS: 19741-14-1

METHOTREXATE IMPURITY E CRS

Ref: 41-Y0000664

4-[[(2,4-diamino-6-pteridinyl)methyl](methyl)amino]benzenecarboxylic acid

CAS: 19741-14-1

Formula: C₁₅H₁₅N₇O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 325.3253

Ref: IN-DA0073DD

4-(((2,4-Diaminopteridin-6-Yl)Methyl)(Methyl)Amino)Benzoic Acid

CAS: 19741-14-1

4-(((2,4-Diaminopteridin-6-Yl)Methyl)(Methyl)Amino)Benzoic Acid

Purity: 98%

Molecular weight: 325.33g/mol

Ref: 54-OR1011080

Methotrexate metabolite

CAS: 19741-14-1

Methotrexate metabolite

Purity: ≥95%

Molecular weight: 325.33g/mol

Ref: 54-BUP13960

4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoic Acid (4-Amino-N10-methylpteroic Acid; APA)

CAS: 19741-14-1

Color and Shape: Neat

Ref: 86-MM0040.02

Methotrexate metabolite

CAS: 19741-14-1

DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.

Formula: C₁₅H₁₅N₇O₂

Purity: 95.60% - 97.59%

Color and Shape: Solid

Molecular weight: 325.33

Ref: TM-T16045

Methotrexate EP Impurity E (Methotrexate USP Related Compound E (Free Form))

CAS: 19741-14-1

Formula: C₁₅H₁₅N₇O₂

Molecular weight: 325.33

Ref: 4Z-M-706

DAMPA

Controlled Product

CAS: 19741-14-1

Impurity Methotrexate EP Impurity E
Stability Hygroscopic
Applications DAMPA is a Methotrexate (M260675) analog (1). DAMPA is an antitumor agent (2).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Martinelli, J. et al.: J. Med. Chem. 1979 Jul;22(7):869-742. Oudart, J. et al.: Ann Biol Clin (Paris). 2016 Jun 1;74(3):333-7

Formula: C₁₅H₁₅N₇O₂

Color and Shape: Dark Yellow To Dark Brown

Molecular weight: 325.33

Ref: TR-D136500

Methotrexate EP Impurity E

CAS: 19741-14-1

Formula: C₁₅H₁₅N₇O₂

Molecular weight: 325.33

Ref: ST-EA-CP-M12005

4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid

CAS: 19741-14-1

4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid is a drug with low bioavailability. It is used to treat leishmaniasis, an infection caused by the parasite Leishmania. 4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid inhibits the synthesis of folic acid by blocking the enzyme dihydrofolate reductase in the bacteria. This drug also has been shown to be effective against autoimmune diseases and inflammatory bowel disease. The terminal half-life of 4-[(2,4-diamino6 pteridinyl)methyl]methylamino benzoic acid is approximately 5 hours and it can be detected in urine for up to 12 hours after administration.

Formula: C₁₅H₁₅N₇O₂

Purity: (1H-Nmr) Min. 95 Area-%

Color and Shape: Brown Yellow Powder

Molecular weight: 325.33 g/mol

Ref: 3D-ID20780

4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid

CAS: 19741-14-1

Formula: C₁₅H₁₅N₇O₂

Purity: 95%

Molecular weight: 325.332

Ref: 10-F320000