CAS 197587-31-8

HEPTAKIS(6-O-SULFO)-(BETA)-CYCLODEXTRIN

Description:

Heptakis(6-O-sulfo)-β-cyclodextrin is a modified cyclodextrin, which is a cyclic oligosaccharide composed of seven glucose units linked by α-1,4-glycosidic bonds. This particular compound features sulfonate groups at the 6-position of the glucose units, enhancing its solubility in water and its ability to form inclusion complexes with various hydrophobic molecules. The sulfonation increases the compound's polarity and can improve its interaction with biological systems, making it useful in pharmaceutical applications, particularly for drug delivery and solubilization of poorly soluble drugs. Heptakis(6-O-sulfo)-β-cyclodextrin exhibits properties such as biocompatibility, low toxicity, and the ability to stabilize guest molecules, which can enhance their bioavailability. Its unique structure allows it to encapsulate a wide range of compounds, making it valuable in various fields, including medicine, food science, and environmental applications. Overall, this compound represents a versatile tool in enhancing the solubility and delivery of therapeutic agents.

Formula: C₄₂H₆₃Na₇O₅₆S₇

InChI: InChI=1/C42H70O56S7.7Na/c43-15-22(50)36-85-8(1-78-99(57,58)59)29(15)92-37-23(51)16(44)31(10(86-37)3-80-101(63,64)65)94-39-25(53)18(46)33(12(88-39)5-82-103(69,70)71)96-41-27(55)20(48)35(14(90-41)7-84-105(75,76)77)98-42-28(56)21(49)34(13(91-42)6-83-104(72,73)74)97-40-26(54)19(47)32(11(89-40)4-81-102(66,67)68)95-38-24(52)17(45)30(93-36)9(87-38)2-79-100(60,61)62;;;;;;;/h8-56H,1-7H2,(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77);;;;;;;/q;7*+1/p-7/t8?,9?,10?,11?,12?,13?,14?,15-,16-,17-,18-,19-,20-,21-,22+,23+,24+,25+,26+,27+,28+,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42+;;;;;;;/m1......./s1/rC42H63Na7O56S7/c43-99-106(64,65)78-1-8-29-15(50)22(57)36(85-8)93-30-9(2-79-107(66,67)100-44)87-38(24(59)17(30)52)95-32-11(4-81-109(70,71)102-46)89-40(26(61)19(32)54)97-34-13(6-83-111(74,75)104-48)91-42(28(63)21(34)56)98-35-14(7-84-112(76,77)105-49)90-41(27(62)20(35)55)96-33-12(5-82-110(72,73)103-47)88-39(25(60)18(33)53)94-31-10(3-80-108(68,69)101-45)86-37(92-29)23(58)16(31)51/h8-42,50-63H,1-7H2/t8?,9?,10?,11?,12?,13?,14?,15-,16-,17-,18-,19-,20-,21-,22+,23+,24+,25+,26+,27+,28+,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42+/m1/s1

SMILES: C(C1C2C(C(C(O1)OC1C(COS(=O)(=O)O)OC(C(C1O)O)OC1C(COS(=O)(=O)O)OC(C(C1O)O)OC1C(COS(=O)(=O)O)OC(C(C1O)O)OC1C(COS(=O)(=O)O)OC(C(C1O)O)OC1C(COS(=O)(=O)O)OC(C(C1O)O)OC1C(COS(=O)(=O)O)OC(C(C1O)O)O2)O)O)OS(=O)(=O)O.[Na].[Na].[Na].[Na].[Na].[Na].[Na]

Synonyms:

• Heptakis(6-O-Sulfo)-(Beta)-Cyclodextrin Heptasodium Salt 98%
• 6-O-Sulfo-Β-Cyclodextrin Sodium Salt
• Heptakis(6-O-Sulfo)-Β-Cyclodextrin Heptasodium Salt
• Hs--CD
• 6-O-Sulfo-β-cyclodextrin sodium salt, Hs-β-CD

6-O-Sulfo-β-cyclodextrin (sodium salt)

CAS: 197587-31-8

6-O-Sulfo-β-cyclodextrin is a sulfated cyclodextrin.1It has been used for the chiral separation of nadolol racemates by capillary electrophoresis.

Formula: C₄₂H₆₃Na₇O₅₆S₇

Color and Shape: Solid

Molecular weight: 1849.3

Ref: TM-T37812

Heptakis(6-sulfo)-β-cyclodextrin sodium salt

CAS: 197587-31-8

Heptakis(6-sulfo)-β-cyclodextrin sodium salt

Ref: 54-BICY1030

Heptakis(6-O-sulfo)-β-cyclodextrin Heptasodium Salt (>90%)

Controlled Product

CAS: 197587-31-8

Applications A β-Cyclodextrin derivative that inhibits anthrax lethal toxin. Chiral selector for capillary electrophorese, CE1.
References Friedlander, A., et al.: J. Biol. Chem., 261, 7123 (1986), Finkelstein, A., et al.: Toxicology, 87, 29 (1994), Benson, E., et al.: Biochemistry, 37, 3941 (1998), Brossier, F., et al.: Toxicon, 39, 1747 (2001),

Formula: C₄₂H₆₃O₅₆S₇·7Na

Purity: >90%

Color and Shape: Neat

Molecular weight: 1849.30

Ref: TR-H281125

6-O-Sulfo-β-cyclodextrin sodium

CAS: 197587-31-8

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formula: C₄₂H₆₃Na₇O₅₆S₇

Purity: (%) Min. 95%

Color and Shape: Powder

Molecular weight: 1,849.31 g/mol

Ref: 3D-OH23758