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CAS 197632-76-1

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FMOC-N-ME-LYS(BOC)-OH

Description:
FMOC-N-ME-LYS(BOC)-OH, also known as Fmoc-N-methyl-Lysine (Boc)-OH, is a protected amino acid commonly used in peptide synthesis. It features a fluorenylmethyloxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The presence of a tert-butyloxycarbonyl (Boc) group on the lysine side chain provides additional protection for the amino group of lysine, enhancing the stability of the molecule during synthesis. This compound is characterized by its solubility in organic solvents, such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), while being less soluble in water. Its structure allows for the introduction of a methyl group at the nitrogen of the lysine side chain, which can influence the peptide's properties, such as its hydrophobicity and steric hindrance. FMOC-N-ME-LYS(BOC)-OH is widely utilized in solid-phase peptide synthesis and is valuable in the development of peptides for research and therapeutic applications.
Formula:C27H34N2O6
Synonyms:
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N-Alpha-Methyl-N-Epsilon-T-Butyl-Oxycarbonyl-L-Lysine
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N-Alpha-Methyl-N-Epsilon-Tert-Butyloxycarbonyl-L-Lysine
  • Fmoc-N-Alpha-Methyl-N-Epsilon-T-Boc-L-Lysine
  • Fmoc-Melys(Boc)-Oh
  • Fmoc-L-Melys(Boc)-Oh
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50
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90
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100
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