CAS 19767-45-4: Mesna
Description:Mesna, or 2-mercaptoethanesulfonate, is a synthetic thiol compound primarily used as a chemoprotective agent in oncology. It is characterized by its ability to detoxify harmful metabolites of certain chemotherapeutic agents, particularly ifosfamide and cyclophosphamide, thereby reducing the risk of hemorrhagic cystitis. Mesna is a water-soluble compound, which allows for easy administration via intravenous or oral routes. Its mechanism of action involves the conjugation of its thiol group with toxic metabolites, facilitating their excretion through the urine. Mesna is generally well-tolerated, with a low incidence of side effects, although some patients may experience mild gastrointestinal disturbances. The compound is often administered alongside chemotherapy regimens to enhance patient safety and treatment efficacy. Its chemical structure includes a sulfonate group, which contributes to its solubility and reactivity. Overall, Mesna plays a crucial role in supportive cancer care, helping to mitigate the adverse effects of certain chemotherapeutic agents.
Formula:C2H6O3S2·Na
InChI:InChI=1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);
InChI key:InChIKey=PYTISYCTLQTCTM-UHFFFAOYSA-N
SMILES:[Na].O=S(=O)(O)CCS
- Synonyms:
- 2-Mercapto-1-ethanesulfonic acid monosodium salt
- 2-Mercaptoethanesulfonic acid monosodium salt
- 2-Mercaptoethanesulfonic acid sodium salt
- 2-Mercaptoethanesulphonicacid,sodiumsalt
- D 7093
- Ethanesulfonic Acid, 2-Mercapto-, Sodium Salt (1:1)
- Ethanesulfonic acid, 2-mercapto-, monosodium salt
- Mesna
- Mesnex
- Mesnum
- See more synonyms
- Mistabron
- Mistabronco
- Mitexan
- Mucofluid
- Prehepon
- Sodium 2-Sulfanylethanesulfonate
- Ucb 3983
- Uromitexan
- Sodium 2-mercaptoethanesulfonate
