CAS 1977-07-7

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

Description:

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine, identified by its CAS number 1977-07-7, is a chemical compound that belongs to the class of dibenzo diazepines. This substance features a complex polycyclic structure, which includes two fused benzene rings and a diazepine ring, contributing to its unique chemical properties. The presence of a piperazine moiety enhances its pharmacological profile, often associated with psychoactive effects. Typically, compounds of this nature exhibit a range of biological activities, including potential anxiolytic, antidepressant, or antipsychotic effects, due to their interaction with neurotransmitter systems in the brain. The compound's solubility, stability, and reactivity can vary based on its molecular structure and substituents, influencing its application in medicinal chemistry. Safety and handling precautions are essential when working with this compound, as with many psychoactive substances, due to potential toxicity and regulatory considerations. Overall, 11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine represents a significant area of interest in pharmaceutical research.

Formula: C₁₈H₂₀N₄

InChI: InChI=1/C18H20N4/c1-21-10-12-22(13-11-21)18-14-6-2-3-7-15(14)19-16-8-4-5-9-17(16)20-18/h2-9,19H,10-13H2,1H3

SMILES: CN1CCN(CC1)C1=Nc2ccccc2Nc2ccccc12

Synonyms:

• Brn 0761696
• 5H-Dibenzo(b,e)(1,4)diazepine, 11-(4-methyl-1-piperazinyl)-
• 11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
• 11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
• 5-25-11-00363 (Beilstein Handbook Reference)
• Dechloroclozapine
• Dopamine serotonin antagonist-1

Deschloroclozapine

CAS: 1977-07-7

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist.

Formula: C₁₈H₂₀N₄

Purity: 99.61% - 99.98%

Color and Shape: Solid

Molecular weight: 292.38

Ref: TM-T11078

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

CAS: 1977-07-7

Formula: C₁₈H₂₀N₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 292.3782

Ref: IN-DA00B4HT

Deschloroclozapine

CAS: 1977-07-7

Deschloroclozapine

Purity: ≥98%

Molecular weight: 292.38g/mol

Ref: 54-BUP06664

Dechloroclozapine

CAS: 1977-07-7

Formula: C₁₈H₂₀N₄

Color and Shape: Yellow Solid

Molecular weight: 292.39

Ref: 4Z-C-1424

Deschloroclozapine

CAS: 1977-07-7

Deschloroclozapine

Purity: 98%

Molecular weight: 292.38g/mol

Ref: 54-OR1023182

11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

CAS: 1977-07-7

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 292.385986328125

Ref: 10-F517620

Deschloro Clozapine

CAS: 1977-07-7

Formula: C₁₈H₂₀N₄

Molecular weight: 292.4

Ref: ST-EA-CP-C63016

Deschloroclozapine

CAS: 1977-07-7

Deschloroclozapine is a potent irreversible inhibitor of the enzyme acetylcholinesterase. Deschloroclozapine reversibly binds to the active site of acetylcholinesterase, inhibiting the breakdown of acetylcholine. This causes an increase in concentration of acetylcholine in the synaptic cleft, which stimulates postsynaptic receptors and leads to increased activation of cholinergic neurons. The drug also inhibits cellular glutathione reductase and has been shown to be insensitive to acetylcholine receptor.

Formula: C₁₈H₂₀N₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 292.38 g/mol

Ref: 3D-BAA97707