CAS 1977-11-3

Perlapine

Description:

Perlapine, with the CAS number 1977-11-3, is a chemical compound that belongs to the class of phenothiazine derivatives. It is primarily recognized for its use in the field of pharmacology, particularly as an antipsychotic agent. The compound exhibits a complex structure that includes a tricyclic system, which is characteristic of many psychotropic medications. Perlapine functions by modulating neurotransmitter activity in the brain, particularly affecting dopamine and serotonin pathways, which can help alleviate symptoms of various psychiatric disorders. In addition to its therapeutic applications, perlapine may also possess other biological activities, including potential anti-inflammatory and analgesic properties. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its efficacy and safety profile. As with many pharmaceuticals, the use of perlapine may be associated with side effects, necessitating careful monitoring during treatment. Overall, perlapine represents a significant compound in the realm of mental health treatment, contributing to the broader understanding of psychopharmacology.

Formula: C₁₉H₂₁N₃

InChI: InChI=1S/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3

InChI key: InChIKey=PWRPUAKXMQAFCJ-UHFFFAOYSA-N

SMILES: CN1CCN(C=2C=3C(CC=4C(N2)=CC=CC4)=CC=CC3)CC1

Synonyms:

• 11H-Dibenz[b,e]azepine, 6- (4-methyl-1-piperazinyl)-
• 1977-11-3
• 6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepine
• 6-(4-Methyl-1-piperazinyl)-11H-dibenzo[b,e]azepine
• 6-(4-Methyl-1-piperazinyl)morphanthridine
• 6-(4-Methylpiperazin-1-yl)-11H-dibenzo[b,e]azepine
• Aw 142333
• Hf 2333
• Hypnodin
• Morphanthridine, 6-(4-methyl-1-piperazinyl)-
• Mp 11
• NSC 291840
• Perlapine

Perlapine

CAS: 1977-11-3

Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).

Formula: C₁₉H₂₁N₃

Color and Shape: Solid

Molecular weight: 291.39

Ref: TM-T33937

Perlapine

Controlled Product

CAS: 1977-11-3

Formula: C₁₉H₂₁N₃

Color and Shape: Neat

Molecular weight: 291.39

Ref: TR-N900420

Perlapine

CAS: 1977-11-3

Perlapine is a drug that binds to the central benzodiazepine receptor and inhibits the binding of ligands to this receptor. Perlapine is used in the treatment of neurological disorders, such as Parkinson's disease and chronic lymphocytic leukemia. It has also been shown to have strong inhibitory effects on serum prolactin levels in rats. The exact mechanism of action for perlapine is unknown, but it has been shown to bind to nitrogen atoms and may be an acetylcholine antagonist or nicotinic acetylcholine receptor antagonist.

Formula: C₁₉H₂₁N₃

Purity: Min. 95%

Molecular weight: 291.4 g/mol

Ref: 3D-BAA97711

Perlapine

CAS: 1977-11-3

Color and Shape: Neat

Ref: 61-FOR3180.00