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CAS 19778-24-6

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Norethindrone Sulfate

Description:
Norethindrone sulfate is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapy. It is a derivative of norethindrone, which is a synthetic form of the naturally occurring hormone progesterone. The chemical structure of norethindrone sulfate includes a steroid backbone, which is characteristic of progestins, and it features a sulfate group that enhances its solubility and bioavailability. This compound is typically administered orally and is known for its ability to regulate menstrual cycles, prevent ovulation, and treat various gynecological disorders. Norethindrone sulfate exhibits anti-estrogenic properties and can influence the endometrial lining, making it effective in managing conditions such as endometriosis and abnormal uterine bleeding. Its pharmacokinetics involve metabolism primarily in the liver, and it is excreted through urine. As with any medication, it may have side effects, including changes in mood, weight gain, and potential cardiovascular risks, necessitating careful consideration and monitoring during use.
Formula:C20H25NaO5S
InChI:InChI=1/C20H26O5S.Na/c1-3-20(25-26(22,23)24)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2;/h1,12,15-18H,4-11H2,2H3,(H,22,23,24);/q;+1/p-1/t15-,16+,17+,18-,19-,20-;/m0./s1/rC20H25NaO5S/c1-3-20(25-27(23,24)26-21)11-9-18-17-6-4-13-12-14(22)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1
SMILES:C#CC1(CCC2C3CCC4=CC(=O)CCC4C3CCC12C)OS(=O)(=O)O.[Na]
Synonyms:
  • (17a)-17-(Sulfooxy)-19-norpregn-4-en-20-yn-3-one
  • 17-Hydroxy-19-nor-17a-pregn-4-en-20-yn-3-one Hydrogen Sulfate
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