CAS 19794-93-5

Trazodone

Description:

Trazodone is an antidepressant medication primarily used to treat major depressive disorder and, in some cases, anxiety disorders and insomnia. It belongs to the class of drugs known as serotonin modulators, which work by inhibiting the reuptake of serotonin in the brain, thereby enhancing mood and emotional balance. Trazodone is characterized by its relatively low potential for abuse compared to other antidepressants, making it a preferred option for patients with a history of substance use disorders. The chemical structure of trazodone includes a triazolopyridine core, which contributes to its pharmacological effects. It is typically administered orally and is known for its sedative properties, often leading to its off-label use as a sleep aid. Common side effects may include drowsiness, dizziness, dry mouth, and gastrointestinal disturbances. Due to its effects on serotonin levels, trazodone should be used cautiously in conjunction with other serotonergic medications to avoid the risk of serotonin syndrome. Overall, trazodone is a versatile medication with a unique profile in the treatment of mood disorders.

Formula: C₁₉H₂₂ClN₅O

InChI: InChI=1/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2

InChI key: InChIKey=PHLBKPHSAVXXEF-UHFFFAOYSA-N

SMILES: O=C1N2C(=NN1CCCN3CCN(CC3)C4=CC(Cl)=CC=C4)C=CC=C2

Synonyms:

• 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one
• 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridine-3(2H)-one
• 2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one
• 2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
• Beneficat
• Trazadone
• Trazalon
• Trazodon
• Trazodona
• Trazodone
• s-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(m-chlorophenyl)-1-piperazinyl]propyl]-
• 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-
• 246-855-5
• 19794-93-5
• 2-{3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
• 8-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-6,8,9-triazabicyclo[4.3.0]nona-2,4,9-trien-7-one
• trazon
• trialodine
• desyrel
• Trazodone Hydrochloride 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-tri

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-

CAS: 19794-93-5

Formula: C₁₉H₂₂ClN₅O

Purity: %

Color and Shape: Solid

Molecular weight: 371.8639

Ref: IN-DA002B6W

Trazodone

CAS: 19794-93-5

Trazodone

Purity: ≥98%

Molecular weight: 371.86g/mol

Ref: 54-BUP14231

Trazodone

CAS: 19794-93-5

Trazodone (AF-1161), a 5-HT 2A/2C receptor antagonist, is used as an antidepressant for treating major anxiety disorders and depressive disorder.

Formula: C₁₉H₂₂ClN₅O

Purity: 99.79% - 99.92%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 371.86

Ref: TM-T22442

Trazodone

Controlled Product

CAS: 19794-93-5

Trazodone is a drug that belongs to the class of antidepressants. It is a serotonin antagonist and reuptake inhibitor. Trazodone has been shown to increase 5-HT (serotonin) concentrations in the brain, which may be due to its antagonism of 5-HT2 receptors. The effect of trazodone on human cyp3a4 was examined using a vivo model; it was found that trazodone does not inhibit this enzyme. There are many drug interactions with trazodone, including an increased risk of hypotension in patients taking monoamine oxidase inhibitors or tricyclic antidepressants, and an increased risk of arrhythmias in patients taking class Ia and III antiarrhythmic agents. Trazodone has been shown to be effective for treating depression and diabetic neuropathy. This drug also has the potential to cause cardiac effects, such as ventricular tachycardia and atrial fibrillation.

Formula: C₁₉H₂₂ClN₅O

Purity: Min. 95%

Molecular weight: 371.86 g/mol

Ref: 3D-FT40163