CAS 198080-36-3
:5'-O-(4,4'-DIMETHOXYTRITYL)-5-FLUORO-O4-(2,4,6-TRIMETHYLPHENYL)-2'-DEOXYURIDINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE
Description:
5'-O-(4,4'-Dimethoxytrityl)-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite is a complex nucleoside phosphoramidite used primarily in the synthesis of oligonucleotides. This compound features a deoxyuridine base modified at the 5' position with a dimethoxytrityl protecting group, which is crucial for the selective coupling during oligonucleotide synthesis. The presence of a fluorine atom at the 5-position of the uridine moiety enhances the stability and specificity of the resulting oligonucleotide. Additionally, the 3'-phosphoramidite group, which includes a cyanoethyl and diisopropyl moiety, facilitates the formation of phosphodiester bonds during the synthesis process. The trimethylphenyl substituent contributes to the overall hydrophobic character and may influence the solubility and interaction of the oligonucleotide in biological systems. This compound is typically utilized in research and therapeutic applications, particularly in the development of antisense oligonucleotides and RNA interference technologies. Proper handling and storage conditions are essential due to its reactive nature.
Formula:C48H56FN4O8P
Synonyms:- 5-Fluoro-O4-Tmp-Du Cep
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Found 2 products.
2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite is a nucleoside that has high purity and high quality. It is an anti cancer agent that inhibits the growth of cells by preventing DNA synthesis and RNA synthesis. This product is also used as an antiviral agent for influenza A virus and herpes simplex virus type 1 (HSV1). 2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite is synthesized from ribonucleosides and deoxyribonucleosides. It can be modified to produce monophosphate, diphosphate or triphosphate forms of the nucleotide.</p>Formula:C48H56FN4O8PPurity:Min. 95%Molecular weight:866.95 g/mol
