8-Bromo-5'-O-(4,4'-dimethoxytrityl)-N2-dimethylaminomethylene-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite is a specialized chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a deoxyguanosine base, which is one of the four nucleobases in DNA, modified with a bromine atom and a dimethoxytrityl protecting group at the 5' position, enhancing its stability and solubility. The presence of a phosphoramidite group allows for its incorporation into growing oligonucleotide chains during solid-phase synthesis. The cyanoethyl and diisopropyl groups contribute to the compound's reactivity and solubility, making it suitable for automated synthesis processes. Overall, this compound is characterized by its complex structure, which facilitates the precise assembly of DNA sequences for research and therapeutic applications, including gene synthesis and molecular diagnostics. Its CAS number, 198080-37-4, uniquely identifies it in chemical databases, aiding in its recognition and procurement for laboratory use.

8-BROMO-5'-O-(4,4'-DIMETHOXYTRITYL)-N2-DIMETHYLAMINOMETHYLENE-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

198080-37-4: 8-Bromo-5'-O-(4,4'-dimethoxytrityl)-N2-dimethylaminomethylene-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite is a specialized chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a deoxyguanosine base, which is one of the four nucleobases in DNA, modified with a bromine atom and a dimethoxytrityl protecting group at the 5' position, enhancing its stability and solubility. The presence of a phosphoramidite group allows for its incorporation into growing oligonucleotide chains during solid-phase synthesis. The cyanoethyl and diisopropyl groups contribute to the compound's reactivity and solubility, making it suitable for automated synthesis processes. Overall, this compound is characterized by its complex structure, which facilitates the precise assembly of DNA sequences for research and therapeutic applications, including gene synthesis and molecular diagnostics. Its CAS number, 198080-37-4, uniquely identifies it in chemical databases, aiding in its recognition and procurement for laboratory use.

8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT guanosine 3'-CE phosphoramidite is a novel synthetic phosphoramidite and activator for the synthesis of oligodeoxynucleotides. The product is a white to off-white powder with a purity of 99% and an average molecular weight of 635.8. It has been used in the synthesis of oligonucleotides as an activator and monophosphate, including DNA, RNA, and PNA (peptide nucleic acid). 8-Bromo-2'-deoxy-N2-DMF 5'-O DMT guanosine 3'-CE phosphoramidite may be used as an anticancer drug or antiviral agent.

CAS 198080-37-4

8-BROMO-5'-O-(4,4'-DIMETHOXYTRITYL)-N2-DIMETHYLAMINOMETHYLENE-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite

Ref: 3D-PB09119