CAS 19817-07-3

1-Azabicyclo[2.2.2]octan-3-ol, 3-ethynyl- (9CI)

Description:

1-Azabicyclo[2.2.2]octan-3-ol, 3-ethynyl- (9CI), with the CAS number 19817-07-3, is a bicyclic compound characterized by its unique structure that includes a nitrogen atom within a bicyclic framework. This compound features a hydroxyl group (-OH) and an ethynyl group (-C≡CH) attached to the bicyclic system, which contributes to its reactivity and potential applications in organic synthesis and medicinal chemistry. The presence of the nitrogen atom in the bicyclic structure imparts basic properties, allowing it to participate in various chemical reactions, including nucleophilic substitutions and cyclizations. Additionally, the ethynyl group can serve as a versatile functional handle for further chemical modifications. The compound's stereochemistry and functional groups may influence its biological activity, making it of interest in pharmacological research. Overall, 1-Azabicyclo[2.2.2]octan-3-ol, 3-ethynyl- is a valuable compound in the field of organic chemistry, with potential applications in drug development and synthesis.

Formula: C₉H₁₃NO

3-ethynyl-1-Azabicyclo[2.2.2]octan-3-ol

CAS: 19817-07-3

Formula: C₉H₁₃NO

Molecular weight: 151.2056

Ref: IN-DA002BCF

3-Ethynyl-1-azabicyclo[2.2.2]octan-3-ol

CAS: 19817-07-3

3-Ethynyl-1-azabicyclo[2.2.2]octan-3-ol is a potent inhibitor of farnesyl diphosphate synthase, an enzyme involved in the biosynthesis of cholesterol. It also has potent inhibitory activity against muscarinic acetylcholine receptors and antimuscarinic effects on the bladder. 3-Ethynyl-1-azabicyclo[2.2.2]octan-3-ol is rapidly absorbed from the gastrointestinal tract and catalyses the nonenzymatic conversion of low density lipoproteins (LDL) to oxidized LDL, which is then taken up by macrophages in the arterial wall where it promotes foam cell formation and atherosclerosis. This drug also inhibits cerebral function and has been shown to have antitumor properties in animal studies.

Formula: C₉H₁₃NO

Purity: Min. 95%

Molecular weight: 151.21 g/mol

Ref: 3D-UAA81707