CAS 1982-36-1

Homochlorcyclizine dihydrochloride

Description:

Homochlorcyclizine dihydrochloride is a chemical compound primarily used for its antihistaminic properties. It is a derivative of cyclizine, which is known for its effectiveness in treating motion sickness and allergies. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Its mechanism of action involves blocking histamine H1 receptors, thereby alleviating symptoms associated with allergic reactions and motion sickness. The dihydrochloride form indicates the presence of two hydrochloride groups, which can enhance the compound's solubility and stability. As with many antihistamines, potential side effects may include drowsiness, dry mouth, and dizziness. Proper handling and dosage are essential to minimize adverse effects and ensure therapeutic efficacy. Due to its pharmacological properties, homochlorcyclizine dihydrochloride is often utilized in clinical settings, but it should be used under medical supervision to ensure safety and effectiveness.

Formula: C₁₉H₂₃ClN₂·2ClH

InChI: InChI=1S/C19H23ClN2.2ClH/c1-21-12-5-13-22(15-14-21)19(16-6-3-2-4-7-16)17-8-10-18(20)11-9-17;;/h2-4,6-11,19H,5,12-15H2,1H3;2*1H

InChI key: InChIKey=JLVFQWFTNVMTEG-UHFFFAOYSA-N

SMILES: C(C1=CC=C(Cl)C=C1)(N2CCN(C)CCC2)C3=CC=CC=C3.Cl

Synonyms:

• Homochlorcyclizine hydrochloride
• SA 97 dihydrochloride
• 1H-1,4-Diazepine, 1-[(4-chlorophenyl)phenylmethyl]hexahydro-4-methyl-, hydrochloride (1:2)
• 1H-1,4-Diazepine, 1-[(4-chlorophenyl)phenylmethyl]hexahydro-4-methyl-, dihydrochloride
• 1H-1,4-Diazepine, 1-(p-chloro-α-phenylbenzyl)hexahydro-4-methyl-, dihydrochloride

Homochlorcyclizine Dihydrochloride

CAS: 1982-36-1

Color and Shape: Neat

Ref: 61-FOR3101.01