CAS 1982372-88-2

A-196

CAS: 1982372-88-2

A-196

Purity: ≥98%

Molecular weight: 359.25g/mol

Ref: 54-BUP05604

A-196

CAS: 1982372-88-2

A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over

Formula: C₁₈H₁₆Cl₂N₄

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 359.25

Ref: TM-T4343

A 196

CAS: 1982372-88-2

Selective inhibitor histone methyltransferases SUV420H1 and SUV420H2 (IC50 values = 25 nM and 144 nM, respectively). Reduces histone H4K20me2 and H4K20me3 expression whilst increasing H4K20me1 global expression. Inhibits formation of p53-binding protein 1 (53BP1) foci upon ionizing radiation and reduces NHEJ-mediated DNA-break repair.

Formula: C₁₈H₁₆Cl₂N₄

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 359.25 g/mol

Ref: 3D-BA164085