CAS 198284-64-9

GAP 27

Description:

GAP 27, with the CAS number 198284-64-9, is a synthetic compound that functions primarily as a selective inhibitor of the protein kinase G (PKG) pathway. It is known for its role in research related to cardiovascular physiology and cellular signaling. GAP 27 is characterized by its ability to interfere with the interaction between PKG and its substrates, thereby modulating various physiological processes, including vascular smooth muscle relaxation and platelet function. The compound is often utilized in experimental settings to elucidate the mechanisms of PKG signaling and its implications in diseases such as hypertension and heart failure. In terms of its chemical properties, GAP 27 is typically presented as a solid at room temperature and is soluble in organic solvents, making it suitable for various laboratory applications. As with many research chemicals, safety data sheets should be consulted for handling and storage guidelines, as well as potential hazards associated with its use.

Formula: C₆₀H₁₀₂N₁₅O₁₇

Synonyms:

• H-Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile-Ohser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile
• M.W. 1304.55 C60H101N15O17

GAP 27

CAS: 198284-64-9

For cellular and molecular biology applications

Ref: 02-J64109

GAP 27

CAS: 198284-64-9

Formula: C₆₀H₁₀₁N₁₅O₁₇

Purity: 98%

Molecular weight: 1304.5342

Ref: IN-DA00AOLU

Gap 27

CAS: 198284-64-9

Gap 27

Purity: ≥98%

Molecular weight: 1304.53g/mol

Ref: 54-BUP01791

Gap 27

CAS: 198284-64-9

Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.

Formula: C₆₀H₁₀₁N₁₅O₁₇

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 1304.53

Ref: TM-TP1333

GAP 27 acetate salt

CAS: 198284-64-9

GAP 27 is a connexin that is expressed in the cardiac and skin cells. GAP 27 acetate salt H-Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile-OH acetate salt is made up of a number of amino acids, including serine, arginine, proline, glutamic acid, lysine, threonine and isoleucine. It has been shown to have biological function in vivo models and in vitro assays. GAP 27 acetate salt H-Ser-Arg-Pro-Thr-Glu-Lys-Thr--Ile--Phe--Ile--Ile--OH acetate salt has been shown to be non toxic to the heart and skin cells. This protein also shows growth factor activity when it interacts with toll like receptor 4 (TLR4) on human skin cells.

Formula: C₆₀H₁₀₁N₁₅O₁₇

Purity: Min. 95%

Molecular weight: 1,304.53 g/mol

Ref: 3D-FG110171