CAS 19829-31-3

3'-Bromopropiophenone

Description:

3'-Bromopropiophenone, with the CAS number 19829-31-3, is an organic compound that belongs to the class of ketones. It features a bromine atom attached to the aromatic ring of a propiophenone structure, which consists of a phenyl group connected to a propanone moiety. This compound typically appears as a white to off-white solid and is characterized by its moderate solubility in organic solvents such as ethanol and acetone, while being less soluble in water due to its hydrophobic nature. The presence of the bromine substituent can influence its reactivity, making it useful in various chemical synthesis applications, including the production of pharmaceuticals and agrochemicals. Additionally, 3'-Bromopropiophenone can undergo electrophilic aromatic substitution reactions, and its ketone functional group allows for further derivatization. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate protective equipment should be used.

Formula: C₉H₉BrO

InChI: InChI=1/C9H9BrO/c1-2-9(11)7-4-3-5-8(10)6-7/h3-6H,2H2,1H3

InChI key: InChIKey=QSHLXVTVXQTHBS-UHFFFAOYSA-N

SMILES: C(CC)(=O)C1=CC(Br)=CC=C1

Synonyms:

• 1-(3-Bromophenyl)-1-propanone
• 1-(3-Bromophenyl)Propan-1-One
• 1-Propanone, 1-(3-bromophenyl)-
• 3-Bromophenyl ethyl ketone
• Propiophenone, 3′-bromo-
• m-Bromopropiophenone
• 3′-Bromopropiophenone
• LABOTEST-BB LT01143368
• 3''-BROMOPROPIOPHENONE 98%
• 1-(3-bromophenyl)-1-propanon

3'-Bromopropiophenone

CAS: 19829-31-3

Formula: C₉H₉BrO

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 213.07

Ref: 3B-B1888

3'-Bromopropiophenone, 97%

CAS: 19829-31-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₉BrO

Purity: 97%

Color and Shape: Fused solid, White to pale cream

Molecular weight: 213.08

Ref: 02-A16757

1-Propanone, 1-(3-bromophenyl)-

CAS: 19829-31-3

Formula: C₉H₉BrO

Purity: 98%

Color and Shape: Solid

Molecular weight: 213.0712

Ref: IN-DA002BF5

3'-Bromopropiophenone

CAS: 19829-31-3

3'-Bromopropiophenone

Formula: C₉H₉BrO

Purity: 98%

Color and Shape: off white solid

Molecular weight: 213.07g/mol

Ref: 54-OR4291

3'-Bromopropiophenone, min. 98%

CAS: 19829-31-3

Formula: C₉H₉BrO

Purity: min. 98%

Color and Shape: White to off-white solid/ Clear, colorless to very-pale yellow liquid dependent on the temperature

Molecular weight: 213.07

Ref: 08-06-0057

3-Bromopropiophenone

CAS: 19829-31-3

Formula: C₉H₉BrO

Purity: 98%

Color and Shape: Solid

Molecular weight: 213.074

Ref: 10-F114000

3'-Bromopropiophenone

Controlled Product

CAS: 19829-31-3

Applications 3'-Bromopropiophenone is used as a reagent to synthesize kinase spindle protein inhibitors (such as Ispinesib [I918500]) that also act as antitumour agents in vivo. 3'-Bromopropiophenone is also an inhibitor of cruzain, an essential protease that originates in the parasite Trypanosoma cruzi.
References Gillmor, S., et al.: Prot. Sci., 6, 1603 (1997); Leite, A., et al.: ChemMedChem, 2, 1339 (2007); Wang, F., et al.: J. Med. Chem., 55, 1511 (2012)

Formula: C₉H₉BrO

Color and Shape: Neat

Molecular weight: 213.07

Ref: TR-B687240

3-Bromopropiophenone

CAS: 19829-31-3

3-Bromopropiophenone is a chemical compound that is structurally related to the antimalarial drug chloroquine. It has been shown to be a potent inhibitor of parasitic kinases in mammalian cells, with IC50 values in the nanomolar range. 3-Bromopropiophenone has been shown to inhibit the growth of trypanosomes, and can be used as an alternative treatment for this disease. The vibrational spectra and kinetic parameters of 3-bromopropiophenone have also been studied using cell culture and molecular modeling methods. The nature of the isomers formed during the reaction of 3-bromopropiophenone with its substrate have also been investigated using computational methods. 3-Bromopropiophenone inhibits heart disease progression by interacting with parameters such as frequency and heart rate.

Formula: C₉H₉BrO

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 213.07 g/mol

Ref: 3D-FB32610